Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 known ✓ | P03372 | 1/20 | 0.50 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.50 |
| ▸ | PPARG | P37231 | 7/20 | 0.50 |
| ▸ | PPARD | Q03181 | 7/20 | 0.50 |
| ▸ | PPARA | Q07869 | 7/20 | 0.50 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.50 |
| ▸ | TSHR | P16473 | 4/20 | 0.50 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | TLR2 | O60603 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | FABP4 | P15090 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.50 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | PDE4A | P27815 | 1/20 | 0.50 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL10615906 | 1.00 | GPR84 (0.50) | GPR84PPARGPPARDPPARAHDAC11 | |
| Acetic Acid SCHEMBL2572942 | 1.00 | GPR84 (0.50) | GPR84PPARGPPARDPPARAHDAC11 | |
| Acetic Acid SCHEMBL10877763 | 1.00 | GPR84 (0.50) | GPR84PPARGPPARDPPARAHDAC11 | |
| Acetic Acid SCHEMBL2935215 | 0.89 | — | — | |
| Acetic Acid SCHEMBL674468 | 0.89 | AKR1B1 (0.43) | GPR84PPARGPPARDPPARAHDAC11 | |
| SCHEMBL11345896 | 0.87 | KMT2A (0.48) | GPR84PPARGPPARDPPARAHDAC11 | |
| Nonane SCHEMBL23929397 | 0.86 | GPR84 (0.63) | GPR84PPARGPPARDPPARAHDAC11 | |
| Decane SCHEMBL14718768 | 0.86 | GPR84 (0.63) | GPR84PPARGPPARDPPARAHDAC11 | |
| Undecane SCHEMBL14719515 | 0.86 | GPR84 (0.63) | GPR84PPARGPPARDPPARAHDAC11 | |
| Heptane SCHEMBL16058605 | 0.86 | GPR84 (0.63) | GPR84PPARGPPARDPPARAHDAC11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110891993-B | Low temperature curing 1K basecoat and method for coating a substrate with a 1K basecoat | 巴斯夫涂料有限公司 | 2022-11-22 | — | — | CN | disclosed |
| CN-110945085-B | Low temperature cured coatings formed by polarity-promoted catalyst migration between layers in a two-layer cure mechanism | 巴斯夫涂料有限公司 | 2022-07-12 | — | — | CN | disclosed |
| CN-109476811-B | One-part low temperature cure coating formed via a dual layer cure mechanism | 巴斯夫涂料有限公司 | 2022-02-11 | — | — | CN | disclosed |
| CN-109476933-B | Low temperature cured coatings via a dual layer cure mechanism of a pigmented water-based base layer and a solvent-based top layer | 巴斯夫涂料有限公司 | 2021-10-12 | — | — | CN | disclosed |
| CN-109071934-B | Heat-curable composition | 株式会社钟化 | 2021-07-20 | — | — | CN | disclosed |
| CN-111433300-A | Scratch-resistant and scratch-resistant automotive coatings | 巴斯夫涂料有限公司 | 2020-07-17 | — | — | CN | disclosed |
| CN-110997836-A | Two-component (2K) varnish and method for coating a substrate with a two-component (2K) varnish having an enhanced visual appearance | 巴斯夫涂料有限公司 | 2020-04-10 | — | — | CN | disclosed |
| CN-110945085-A | Low temperature cured coatings formed by polarity-promoted catalyst migration between layers in a dual-layer cure mechanism | 巴斯夫涂料有限公司 | 2020-03-31 | — | — | CN | disclosed |
| CN-110891993-A | Low temperature curing 1K basecoat and method of coating a substrate with a 1K basecoat | 巴斯夫涂料有限公司 | 2020-03-17 | — | — | CN | disclosed |
| EP-2384358-B1 | ELECTROCOAT COMPOSITION AND PROCESS REPLACING PHOSPHATE PRETREATMENT | BASF COATINGS GMBH (DE) | 2017-05-24 | — | — | EP | disclosed |
| EP-1798218-A1 | MONOMER COMPOUND, PROCESS FOR PRODUCING THE SAME, POLYMER THEREOF, AND WATER-BASED CURABLE COMPOSITION | KANSAI PAINT CO., LTD. (JP) | 2007-06-20 | — | — | EP | disclosed |
| US-7070859-B2 | Acrylic resin composition organosiloxane resin composition and laminate comprising the same | TEIJIN CHEMICALS, LTD. (JP) | 2006-07-04 | — | — | US | disclosed |
| US-20060124462-A1 | Method of coating with lead-free electrodeposition coating composition and coated article | HONDA MOTOR CO., LTD. (JP) | 2006-06-15 | — | — | US | disclosed |
| EP-1516722-A1 | ACRYLIC RESIN COMPOSITION, ORGANOSILOXANE RESIN COMPOSITION AND LAMINATES MADE BY USING THEM | Teijin Chemicals, Ltd. (JP) | 2005-03-23 | — | — | EP | disclosed |
| US-20040247878-A1 | Acrylic resin composition organosiloxane resin composition and laminate comprising the same | TEIJIN CHEMICALS LTD. (JP) | 2004-12-09 | — | — | US | disclosed |
| WO-2004078856-A1 | LEAD-FREE ELECTRODEPOSITION COATING COMPOSITON AND COATED ARTICLE | HONDA MOTOR CO., LTD. (JP) | 2004-09-16 | — | — | WO | disclosed |
| WO-2004078857-A1 | METHOD OF COATING WITH LEAD-FREE ELECTRODEPOSITION COATING COMPOSITION AND COATED ARTICLE | HONDA MOTOR CO., LTD. (JP) | 2004-09-16 | — | — | WO | disclosed |
| EP-0073835-B1 | PROCESS FOR PRODUCING POLYURETHANE POLYMER | Yoshitomi Pharmaceutical Industries, Ltd. (JP) | 1986-04-09 | — | — | EP | disclosed |
| US-4404352-A | ORGANOTIN COMPOUNDS AS CATALYST AND AMINES TO GIVE CURED COATINGS WITH PARTIALLY BLOCKED ISOCYANATES | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1983-09-13 | — | — | US | disclosed |
| EP-0073835-A1 | PROCESS FOR PRODUCING POLYURETHANE POLYMER | Yoshitomi Pharmaceutical Industries, Ltd. (JP) | 1983-03-16 | — | — | EP | disclosed |