Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 known ✓ | P03372 | 1/20 | 0.42 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | FNTA | P49354 | 1/20 | 0.43 |
| ▸ | FNTB | P49356 | 1/20 | 0.43 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.43 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.42 |
| ▸ | PPARG | P37231 | 7/20 | 0.42 |
| ▸ | PPARD | Q03181 | 7/20 | 0.42 |
| ▸ | PPARA | Q07869 | 7/20 | 0.42 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.42 |
| ▸ | TSHR | P16473 | 4/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | CES1 | P23141 | 3/20 | 0.42 |
| ▸ | TLR2 | O60603 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | FABP4 | P15090 | 2/20 | 0.42 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.42 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL2935215 | 1.00 | — | — | |
| Acetic Acid SCHEMBL10615906 | 0.89 | GPR84 (0.50) | AKR1B1THRBFNTAFNTBPGGT1B | |
| Acetic Acid SCHEMBL2572942 | 0.89 | GPR84 (0.50) | AKR1B1THRBFNTAFNTBPGGT1B | |
| Acetic Acid SCHEMBL10877763 | 0.89 | GPR84 (0.50) | AKR1B1THRBFNTAFNTBPGGT1B | |
| Acetic Acid SCHEMBL2573455 | 0.89 | GPR84 (0.50) | AKR1B1THRBFNTAFNTBPGGT1B | |
| Butanedione SCHEMBL2248860 | 0.88 | CES1 (0.48) | AKR1B1THRBFNTAFNTBPGGT1B | |
| Hydrogen Peroxide SCHEMBL3421295 | 0.87 | — | — | |
| Methacrylic Acid SCHEMBL11220583 | 0.85 | THRB (0.42) | AKR1B1THRBFNTAFNTBPGGT1B | |
| Acetic Acid SCHEMBL10894464 | 0.84 | — | — | |
| Fumaric Acid SCHEMBL2940731 | 0.81 | HCAR2 (0.52) | THRBTSHRTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 186 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5688890-A | Thermoplastic polyurethane composition | KURARAY CO., LTD. (JP) | 1997-11-18 | — | — | US | claimed |
| JP-5302007-A | — | — | None | — | — | JP | disclosed |
| JP-6248060-A | — | — | None | — | — | JP | disclosed |
| US-12570785-B2 | Thermoplastic polyurethane resin elastomers | MITSUBISHI CHEMICAL CORPORATION (JP) | 2026-03-10 | — | — | US | disclosed |
| EP-3889199-B1 | POLYESTER POLYOL AND POLYURETHANE | DAICEL CORP (JP) | 2025-08-20 | — | — | EP | disclosed |
| US-20240392060-A1 | COMPOSITION FOR POLYURETHANE ELASTOMER, AND POLYURETHANE ELASTOMER | DAICEL CORPORATION (JP) | 2024-11-28 | — | — | US | disclosed |
| US-12071504-B2 | Polyester polyol and polyurethane | DAICEL CORPORATION (JP) | 2024-08-27 | — | — | US | disclosed |
| EP-4403587-A1 | COMPOSITION FOR POLYURETHANE ELASTOMER, AND POLYURETHANE ELASTOMER | Daicel Corporation (JP) | 2024-07-24 | — | — | EP | disclosed |
| CN-117940476-A | Composition for polyurethane elastomer and polyurethane elastomer | 株式会社大赛璐 | 2024-04-26 | — | — | CN | disclosed |
| US-11884837-B2 | Scratch and mar resistant automotive coatings | BASF COATINGS GMBH (DE) | 2024-01-30 | — | — | US | disclosed |
| EP-0073835-B1 | PROCESS FOR PRODUCING POLYURETHANE POLYMER | Yoshitomi Pharmaceutical Industries, Ltd. (JP) | 1986-04-09 | — | — | EP | disclosed |
| EP-0031640-B1 | COMPOSITIONS INCLUDING MERCAPTOORGANOPOLYSILOXANES AND STANNIC SALTS OF CARBOXYLIC ACIDS | DOW CORNING CORPORATION (US) | 1984-02-15 | — | — | EP | disclosed |
| US-4404352-A | ORGANOTIN COMPOUNDS AS CATALYST AND AMINES TO GIVE CURED COATINGS WITH PARTIALLY BLOCKED ISOCYANATES | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1983-09-13 | — | — | US | disclosed |
| EP-0073835-A1 | PROCESS FOR PRODUCING POLYURETHANE POLYMER | Yoshitomi Pharmaceutical Industries, Ltd. (JP) | 1983-03-16 | — | — | EP | disclosed |
| EP-0031640-A2 | Compositions including mercaptoorganopolysiloxanes and stannic salts of carboxylic acids | DOW CORNING CORPORATION (US) | 1981-07-08 | — | — | EP | disclosed |
| US-4273698-A | Self-bonding room temperature vulcanizable silicone rubber compositions | GENERAL ELECTRIC COMPANY (US) | 1981-06-16 | — | — | US | disclosed |
| WO-1981001569-A1 | COMPOSITIONS INCLUDING MERCAPTOORGANOPOLYSILOXANES AND STANNIC SALTS OF CARBOXYLIC ACIDS | DOW CORNING (US) | 1981-06-11 | — | — | WO | disclosed |
| US-4265792-A | Compositions including mercaptoorganopolysiloxanes and stannic salts of carboxylic acids | DOW CORNING CORPORATION (US) | 1981-05-05 | — | — | US | disclosed |
| US-4257932-A | CHAIN STOPPED POLYSILOXANE, FLUID POLYSILOXANE-SILICATE AND A CROSSLINKING AGENT; MOISTURE CURABLE TO FORM GASKETS | GENERAL ELECTRIC COMPANY (US) | 1981-03-24 | — | — | US | disclosed |
| US-4066397-A | CURING POLYETHER-URETHANE | MILLIKEN RESEARCH CORPORATION (US) | 1978-01-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12570785-B2 | Thermoplastic polyurethane resin elastomers | PUF60, INTS9, ADH1C | ESR1 1500/4885AKR1B1 674/4885THRB 3797/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.