Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 2/20 | 0.42 |
| ▸ | CA1 | P00915 | 2/20 | 0.42 |
| ▸ | CA2 | P00918 | 2/20 | 0.42 |
| ▸ | CA7 | P43166 | 2/20 | 0.42 |
| ▸ | CA9 | Q16790 | 2/20 | 0.42 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.42 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.42 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4598114 | 0.81 | KDM4E (0.57) | GAALMNACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL15779058 | 0.81 | GAA (0.51) | GAALMNACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL16049537 | 0.80 | GAA (0.60) | GAALMNACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL17197313 | 0.80 | CYP1A2 (0.56) | GAACYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL16961730 | 0.80 | GAA (0.47) | GAALMNACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL162217 | 0.80 | HPGD (0.53) | GAALMNACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL12078300 | 0.80 | ABL1 (0.58) | GAALMNACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL2365731 | 0.80 | NR4A2 (0.48) | GAALMNACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL21079321 | 0.80 | LMNA (0.56) | GAALMNACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL9081994 | 0.79 | ALDH1A1 (0.49) | GAALMNACYP1A2CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012029942-A1 | CYCLIC AMIDE DERIVATIVE | 大日本住友製薬株式会社 (JP) | 2012-03-08 | — | — | WO | disclosed |