Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 5/20 | 0.42 |
| ▸ | BTK | Q06187 | 1/20 | 0.41 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.39 |
| ▸ | CCR3 | P51677 | 9/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.36 |
| ▸ | PRMT3 | O60678 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 2/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25735208 | 1.00 | NAMPT (0.42) | NAMPTBTKAKR1C3CCR3SLC6A2 | |
| SCHEMBL25735150 | 0.91 | CCR3 (0.41) | NAMPTBTKAKR1C3CCR3SLC6A2 | |
| SCHEMBL25735200 | 0.91 | CCR3 (0.41) | NAMPTBTKAKR1C3CCR3SLC6A2 | |
| SCHEMBL25643988 | 0.87 | NAMPT (0.38) | NAMPTBTKAKR1C3CCR3HTR2A | |
| SCHEMBL25642319 | 0.87 | NAMPT (0.38) | NAMPTBTKAKR1C3CCR3HTR2A | |
| SCHEMBL25735189 | 0.86 | KEAP1 (0.44) | NAMPTBTKCCR3 | |
| SCHEMBL25735158 | 0.86 | KEAP1 (0.44) | NAMPTBTKCCR3 | |
| SCHEMBL25735205 | 0.86 | NAMPT (0.51) | NAMPTBTKCCR3HTR2A | |
| SCHEMBL25735219 | 0.86 | KEAP1 (0.44) | NAMPTBTKCCR3 | |
| SCHEMBL25735161 | 0.86 | NAMPT (0.51) | NAMPTBTKCCR3HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230192651-A1 | Pyrrolidine Derivative and Use Thereof | WANG, ZHEMING (CN) | 2023-06-22 | — | — | US | disclosed |
| US-20230192651-A1 | Pyrrolidine Derivative and Use Thereof | WANG, ZHEMING (CN) | 2023-06-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230192651-A1 | Pyrrolidine Derivative and Use Thereof | NAMPT, NAPRT, NNMT | NAMPT 1/4885BTK 1812/4885AKR1C3 1712/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.