Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.45 |
| ▸ | NPC1 | O15118 | 7/20 | 0.45 |
| ▸ | RAB9A | P51151 | 7/20 | 0.45 |
| ▸ | MAPT | P10636 | 6/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.45 |
| ▸ | HPGD | P15428 | 4/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 3/20 | 0.43 |
| ▸ | GFER | P55789 | 1/20 | 0.42 |
| ▸ | ABL1 | P00519 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | WDR5 | P61964 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25236480 | 0.80 | ALDH1A1 (0.51) | ALDH1A1NPC1RAB9AMAPTSMN1; SMN2 | |
| SCHEMBL31084668 | 0.80 | ALDH1A1 (0.51) | ALDH1A1NPC1RAB9AMAPTSMN1; SMN2 | |
| SCHEMBL25828656 | 0.80 | NMT1 (0.44) | ALDH1A1NPC1RAB9AHPGDCYP1A2 | |
| SCHEMBL10126898 | 0.77 | KDM4E (0.54) | ALDH1A1MAPTSMN1; SMN2HPGDHSD17B10 | |
| SCHEMBL25238198 | 0.76 | SMN1; SMN2 (0.53) | ALDH1A1NPC1RAB9AMAPTSMN1; SMN2 | |
| SCHEMBL7369256 | 0.72 | HTR2A (0.56) | ALDH1A1NPC1RAB9AMAPTSMN1; SMN2 | |
| SCHEMBL125639 | 0.70 | HPGD (0.73) | ALDH1A1NPC1RAB9AMAPTSMN1; SMN2 | |
| SCHEMBL10156591 | 0.70 | ALDH1A1 (0.46) | ALDH1A1MAPTSMN1; SMN2HPGDCYP1A2 | |
| SCHEMBL28767871 | 0.70 | ABL1 (0.44) | ALDH1A1NPC1RAB9AMAPTSMN1; SMN2 | |
| SCHEMBL14355835 | 0.69 | TSHR (0.52) | ALDH1A1MAPTSMN1; SMN2HSD17B10KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023118373-A1 | BENZENE SULFONAMIDE THIAZOLE COMPOUNDS AND THEIR USE FOR THE TREATMENT OF CANCERS | INSERM (Institut National de la Santé et de la Recherche Médicale) (FR) | 2023-06-29 | — | — | WO | disclosed |