Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 1/20 | 0.56 |
| ▸ | TNKS | O95271 | 1/20 | 0.51 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.51 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.51 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.51 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.51 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 3/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.50 |
| ▸ | CES2 | O00748 | 1/20 | 0.48 |
| ▸ | CES1 | P23141 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | KMO | O15229 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.46 |
| ▸ | FEN1 | P39748 | 1/20 | 0.46 |
| ▸ | PARP1 | P09874 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26054651 | 0.95 | AKR1C3 (0.66) | AKR1C3TNKSPARP15PARP14PARP10 | |
| SCHEMBL25736538 | 0.89 | AKR1C3 (0.46) | AKR1C3TNKSPARP15PARP14PARP10 | |
| SCHEMBL7844611 | 0.87 | CES2 (0.67) | NPC1RAB9ACES2CES1KMT2A | |
| SCHEMBL21658556 | 0.85 | CES2 (0.46) | AKR1C3NPC1POLBRAB9ACYP2C9 | |
| SCHEMBL11758979 | 0.84 | CYP3A4 (0.61) | NPC1RAB9ACES2CES1KMT2A | |
| SCHEMBL10031819 | 0.83 | ACHE (0.52) | CYP2C9HDAC8PARP1ACHE | |
| SCHEMBL6682185 | 0.82 | AKR1C3 (0.64) | AKR1C3TNKSPARP15PARP14PARP10 | |
| SCHEMBL22952541 | 0.82 | KAT6A (0.52) | NPC1POLBRAB9AHDAC8ACHE | |
| SCHEMBL3691895 | 0.81 | PARP10 (0.57) | AKR1C3TNKSPARP15PARP14PARP10 | |
| SCHEMBL25719881 | 0.81 | KMT2A (0.54) | KMT2ANR4A1NR4A2NR4A3SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4198632-A1 | ELECTROPHOTOGRAPHIC PHOTORECEPTOR, PROCESS CARTRIDGE, AND IMAGE FORMING APPARATUS | FUJIFILM Business Innovation Corp. (JP) | 2023-06-21 | — | — | EP | disclosed |