SCHEMBL257370 — predicted protein targets

Predicted protein targets (top 12)

	gene	UniProt	supporting neighbours	confidence
▸	KAT2B	Q92831	2/20	0.41

▸	BAZ2B	Q9UIF8	1/20	0.41

▸	PDE4D	Q08499	9/20	0.35

▸	HSD11B1	P28845	5/20	0.34

▸	PDE4A	P27815	5/20	0.33

▸	PDE4B	Q07343	5/20	0.33

▸	PDE4C	Q08493	5/20	0.33

▸	GRM5	P41594	1/20	0.33

▸	PDE5A	O76074	1/20	0.33

▸	WNT3A	P56704	1/20	0.33

▸	RXFP1	Q9HBX9	1/20	0.33

▸	HSD11B2	P80365	1/20	0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL15100752	0.86	HSD11B1 (0.47)	KAT2BBAZ2BHSD11B1HSD11B2
SCHEMBL15090591	0.86	HSD11B1 (0.47)	KAT2BBAZ2BHSD11B1HSD11B2
SCHEMBL15090633	0.78	HSD11B1 (0.48)	PDE4DHSD11B1HSD11B2
SCHEMBL257359	0.78	HSD11B1 (0.48)	PDE4DHSD11B1HSD11B2
SCHEMBL15090539	0.78	HSD11B1 (0.47)	HSD11B1HSD11B2
SCHEMBL15198837	0.78	HSD11B1 (0.47)	HSD11B1HSD11B2
SCHEMBL10046962	0.78	HSD11B1 (0.47)	HSD11B1HSD11B2
SCHEMBL257369	0.75	KAT2B (0.50)	KAT2BBAZ2BPDE4DPDE4APDE4B
SCHEMBL257366	0.74	KAT2B (0.53)	KAT2BBAZ2BPDE4DPDE4APDE4B
SCHEMBL10046793	0.73	HSD11B1 (0.51)	HSD11B1HSD11B2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2012029942-A1	CYCLIC AMIDE DERIVATIVE	大日本住友製薬株式会社 (JP)	2012-03-08	—	—	WO	disclosed