Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.40 |
| ▸ | CFTR | P13569 | 1/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | DPP4 | P27487 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | GABRP | O00591 | 1/20 | 0.38 |
| ▸ | GABRD | O14764 | 1/20 | 0.38 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.38 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.38 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.38 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.38 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31523576 | 0.89 | KDM4E (0.41) | KDM4ENPC1RAB9AMAPK1ALDH1A1 | |
| SCHEMBL3230064 | 0.81 | CFTR (0.53) | KDM4EMAPK1ALDH1A1CFTRMAPT | |
| SCHEMBL1004608 | 0.76 | MAPK1 (0.64) | KDM4ENPC1RAB9AMAPK1MAPT | |
| SCHEMBL9319138 | 0.76 | KDM4E (0.48) | KDM4ENPC1RAB9AALDH1A1CSNK1D | |
| SCHEMBL9319716 | 0.76 | KDM4E (0.48) | KDM4ENPC1RAB9AALDH1A1CSNK1D | |
| SCHEMBL25738013 | 0.75 | BDKRB1 (0.37) | KDM4EMAPK1ALDH1A1MAPTHSD17B10 | |
| SCHEMBL12488360 | 0.75 | MAPK1 (0.51) | KDM4EMAPK1ALDH1A1CFTRMAPT | |
| SCHEMBL30100067 | 0.75 | MAPK1 (0.51) | KDM4EMAPK1ALDH1A1CFTRMAPT | |
| SCHEMBL30041829 | 0.74 | MAPK1 (0.55) | KDM4EMAPK1ALDH1A1CFTRMAPT | |
| SCHEMBL1336127 | 0.74 | MAPK1 (0.55) | KDM4EMAPK1ALDH1A1CFTRMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023109521-A1 | PARP INHIBITOR, PHARMACEUTICAL COMPOSITION COMPRISING SAME, AND USE THEREOF | 凯复(苏州)生物医药有限公司 | 2023-06-22 | — | — | WO | disclosed |