Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BDKRB1 | P46663 | 3/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | ATF1 | P18846 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25738014 | 0.84 | BDKRB1 (0.40) | BDKRB1MAPK1KDM4EALDH1A1LMNA | |
| SCHEMBL25738012 | 0.75 | KDM4E (0.41) | MAPK1KDM4EALDH1A1MAPTHSD17B10 | |
| SCHEMBL31523576 | 0.68 | KDM4E (0.41) | MAPK1KDM4EALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL9319138 | 0.68 | KDM4E (0.48) | KDM4EALDH1A1SMN1; SMN2MAPTHSD17B10 | |
| SCHEMBL9319716 | 0.68 | KDM4E (0.48) | KDM4EALDH1A1SMN1; SMN2MAPTHSD17B10 | |
| SCHEMBL24759806 | 0.68 | KDM4E (0.38) | KDM4EALDH1A1SMN1; SMN2MAPTHSD17B10 | |
| SCHEMBL38655800 | 0.67 | MAPK1 (0.43) | MAPK1KDM4EALDH1A1LMNAMAPT | |
| SCHEMBL23526528 | 0.66 | KDM4E (0.39) | MAPK1KDM4EALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL31524263 | 0.66 | KDM4E (0.39) | MAPK1KDM4EALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL2387665 | 0.66 | SMN1; SMN2 (0.44) | KDM4EALDH1A1LMNASMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023109521-A1 | PARP INHIBITOR, PHARMACEUTICAL COMPOSITION COMPRISING SAME, AND USE THEREOF | 凯复(苏州)生物医药有限公司 | 2023-06-22 | — | — | WO | disclosed |