Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | DPP4 | P27487 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | GABRP | O00591 | 4/20 | 0.45 |
| ▸ | GABRD | O14764 | 4/20 | 0.45 |
| ▸ | GABRA1 | P14867 | 4/20 | 0.45 |
| ▸ | GABRB1 | P18505 | 4/20 | 0.45 |
| ▸ | GABRG2 | P18507 | 4/20 | 0.45 |
| ▸ | GABRB3 | P28472 | 4/20 | 0.45 |
| ▸ | GABRA5 | P31644 | 4/20 | 0.45 |
| ▸ | GABRA3 | P34903 | 4/20 | 0.45 |
| ▸ | GABRA2 | P47869 | 4/20 | 0.45 |
| ▸ | GABRB2 | P47870 | 4/20 | 0.45 |
| ▸ | GABRA4 | P48169 | 4/20 | 0.45 |
| ▸ | GABRE | P78334 | 4/20 | 0.45 |
| ▸ | GABRA6 | Q16445 | 4/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9319716 | 1.00 | KDM4E (0.48) | KDM4EHPGDPKMHSD17B10DPP4 | |
| SCHEMBL10465494 | 0.90 | GABRA1 (0.52) | KDM4EHPGDPKMHSD17B10DPP4 | |
| SCHEMBL10467645 | 0.88 | MAPK1 (0.52) | KDM4EHPGDPKMHSD17B10GABRP | |
| SCHEMBL9318633 | 0.79 | KDM4E (0.49) | KDM4EHPGDNPC1RAB9AGABRP | |
| SCHEMBL9318646 | 0.78 | MAPK1 (0.49) | KDM4EHPGDPKMHSD17B10GABRP | |
| SCHEMBL9400503 | 0.76 | ALDH1A1 (0.50) | KDM4EHSD17B10NPC1RAB9AGABRP | |
| SCHEMBL25738012 | 0.76 | KDM4E (0.41) | KDM4EHPGDPKMHSD17B10DPP4 | |
| SCHEMBL3516119 | 0.76 | BAZ2B (0.49) | KDM4EHPGDDPP4NPC1RAB9A | |
| SCHEMBL26115003 | 0.74 | KDM4E (0.45) | KDM4EHPGDALDH1A1MAPTTSHR | |
| SCHEMBL3230064 | 0.73 | CFTR (0.53) | KDM4EHPGDPKMHSD17B10GABRP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0281943-B1 | Substituted pyridine-2,4-carboxylic acid derivatives, process for their preparation, their use as well as medicaments based on these compounds | HOECHST AG (DE) | 1994-01-12 | — | — | EP | claimed |