Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 10/20 | 0.67 |
| ▸ | GSPT1 | P15170 | 2/20 | 0.64 |
| ▸ | DDB1 | Q16531 | 2/20 | 0.64 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.64 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.64 |
| ▸ | IKZF3 | Q9UKT9 | 1/20 | 0.62 |
| ▸ | IKZF2 | Q9UKS7 | 10/20 | 0.59 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29480083 | 0.91 | CRBN (0.65) | CRBNGSPT1DDB1CYP2C19KCNH2 | |
| SCHEMBL17432016 | 0.91 | CRBN (0.65) | CRBNGSPT1DDB1CYP2C19KCNH2 | |
| SCHEMBL15128599 | 0.91 | CRBN (0.68) | CRBNGSPT1DDB1CYP2C19KCNH2 | |
| SCHEMBL30496980 | 0.89 | CRBN (0.66) | CRBNGSPT1DDB1CYP2C19KCNH2 | |
| SCHEMBL19172833 | 0.89 | CRBN (0.62) | CRBNGSPT1DDB1CYP2C19KCNH2 | |
| SCHEMBL19116714 | 0.89 | CRBN (0.62) | CRBNGSPT1DDB1CYP2C19KCNH2 | |
| SCHEMBL25228921 | 0.88 | CRBN (0.70) | CRBNGSPT1DDB1CYP2C19KCNH2 | |
| SCHEMBL24741264 | 0.88 | IKZF2 (0.61) | CRBNGSPT1DDB1CYP2C19KCNH2 | |
| SCHEMBL22609589 | 0.88 | CRBN (0.70) | CRBNGSPT1DDB1CYP2C19KCNH2 | |
| SCHEMBL30241950 | 0.88 | CRBN (0.70) | CRBNGSPT1DDB1CYP2C19KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023122581-A2 | IKAROS ZINC FINGER FAMILY DEGRADERS AND USES THEREOF | GILEAD SCIENCES, INC. (US) | 2023-06-29 | — | — | WO | disclosed |