Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 11/20 | 0.65 |
| ▸ | DDB1 | Q16531 | 3/20 | 0.63 |
| ▸ | GSPT1 | P15170 | 2/20 | 0.63 |
| ▸ | IKZF3 | Q9UKT9 | 1/20 | 0.63 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.61 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.61 |
| ▸ | IKZF2 | Q9UKS7 | 9/20 | 0.61 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17432016 | 1.00 | CRBN (0.65) | CRBNDDB1GSPT1IKZF3CYP2C19 | |
| SCHEMBL17423633 | 0.91 | CRBN (0.65) | CRBNDDB1GSPT1IKZF3CYP2C19 | |
| SCHEMBL25740848 | 0.91 | CRBN (0.67) | CRBNDDB1GSPT1IKZF3CYP2C19 | |
| Hydrochloric Acid SCHEMBL17420696 | 0.90 | CRBN (0.64) | CRBNDDB1GSPT1IKZF3CYP2C19 | |
| SCHEMBL25516162 | 0.89 | CRBN (0.52) | CRBNDDB1GSPT1IKZF3CYP2C19 | |
| SCHEMBL15128599 | 0.89 | CRBN (0.68) | CRBNDDB1GSPT1IKZF3CYP2C19 | |
| SCHEMBL24741264 | 0.88 | IKZF2 (0.61) | CRBNDDB1GSPT1IKZF3CYP2C19 | |
| SCHEMBL23657092 | 0.88 | CRBN (0.61) | CRBNDDB1GSPT1IKZF3CYP2C19 | |
| SCHEMBL25469611 | 0.87 | CRBN (0.69) | CRBNDDB1GSPT1IKZF3CYP2C19 | |
| SCHEMBL15128601 | 0.87 | CRBN (0.69) | CRBNDDB1GSPT1IKZF3CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4225749-A1 | COMPOUNDS AND METHODS OF TREATING CANCERS | Cullgen (Shanghai), Inc. (CN) | 2023-08-16 | — | — | EP | disclosed |
| CN-116583509-A | Compounds and methods for treating cancer | 上海睿跃生物科技有限公司 | 2023-08-11 | — | — | CN | disclosed |
| CN-114262319-B | Bifunctional molecule, preparation method and application thereof | 南昌奥瑞药业有限公司 | 2023-05-05 | — | — | CN | disclosed |
| WO-2022073469-A1 | COMPOUNDS AND METHODS OF TREATING CANCERS | CULLGEN (SHANGHAI) , INC. (CN) | 2022-04-14 | — | — | WO | disclosed |
| CN-114262319-A | Bifunctional molecules, preparation method and application thereof | 南昌奥瑞药业有限公司 | 2022-04-01 | — | — | CN | disclosed |