Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.44 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.44 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.41 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | CPB1 | P15086 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18681661 | 1.00 | ACHE (0.44) | ACHEMCL1SRD5A2KCNH2MTNR1A | |
| SCHEMBL25740890 | 1.00 | ACHE (0.44) | ACHEMCL1SRD5A2KCNH2MTNR1A | |
| SCHEMBL12050567 | 0.89 | ACHE (0.46) | ACHEMCL1KCNH2HTR2ACPB1 | |
| SCHEMBL14614304 | 0.83 | ACHE (0.46) | ACHEMCL1KCNH2HTR2ACPB1 | |
| SCHEMBL12203781 | 0.83 | KDM2B (0.51) | ALDH1A1MEN1KMT2A | |
| SCHEMBL3113279 | 0.83 | SRD5A2 (0.58) | MCL1SRD5A2KCNH2HTR2ACPB1 | |
| SCHEMBL1865563 | 0.82 | AKR1C3 (0.49) | MCL1SRD5A2MTNR1AMTNR1BHTR2A | |
| SCHEMBL1865557 | 0.82 | AKR1C3 (0.49) | MCL1SRD5A2MTNR1AMTNR1BHTR2A | |
| SCHEMBL1865559 | 0.82 | AKR1C3 (0.49) | MCL1SRD5A2MTNR1AMTNR1BHTR2A | |
| SCHEMBL8815571 | 0.81 | MCL1 (0.45) | MCL1SRD5A2MTNR1AMTNR1BHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023122581-A2 | IKAROS ZINC FINGER FAMILY DEGRADERS AND USES THEREOF | GILEAD SCIENCES, INC. (US) | 2023-06-29 | — | — | WO | disclosed |