Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.47 |
| ▸ | MPO | P05164 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | NQO2 | P16083 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | APP | P05067 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | HBB | P68871 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31391492 | 1.00 | NPSR1 (0.47) | NPSR1MPOKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL25284840 | 0.86 | POLB (0.54) | KDM4EALDH1A1SMN1; SMN2POLBLMNA | |
| SCHEMBL30466795 | 0.86 | POLB (0.54) | KDM4EALDH1A1SMN1; SMN2POLBLMNA | |
| SCHEMBL9283331 | 0.82 | NPSR1 (0.60) | NPSR1MPOKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL8145986 | 0.81 | NPSR1 (0.48) | NPSR1MPOKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL857219 | 0.79 | KDM4E (0.49) | NPSR1MPOKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL20813453 | 0.79 | APP (0.48) | NPSR1MPOKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL30640287 | 0.79 | KDM4E (0.49) | NPSR1MPOKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL14819968 | 0.79 | DHFR (0.52) | NPSR1MPOKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL31391484 | 0.78 | CYP1A2 (0.41) | KDM4EALDH1A1LMNANQO2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023118507-A2 | COMPOUNDS AND USE THEREOF AS HDAC6 INHIBITORS | AUGUSTINE THERAPEUTICS (BE) | 2023-06-29 | — | — | WO | disclosed |