Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | MPO | P05164 | 1/20 | 0.47 |
| ▸ | ACHE | P22303 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | NQO2 | P16083 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | VDR | P11473 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.44 |
| ▸ | AHR | P35869 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8131948 | 0.86 | KDM4E (0.51) | KDM4EALDH1A1SMN1; SMN2LMNAPOLB | |
| SCHEMBL9283331 | 0.84 | NPSR1 (0.60) | NPSR1MPOACHEKDM4EALDH1A1 | |
| SCHEMBL8149547 | 0.82 | ACHE (0.47) | NPSR1MPOACHEKDM4EALDH1A1 | |
| SCHEMBL25746271 | 0.81 | NPSR1 (0.47) | NPSR1MPOACHEKDM4EALDH1A1 | |
| SCHEMBL20813453 | 0.81 | APP (0.48) | NPSR1MPOACHEKDM4EALDH1A1 | |
| SCHEMBL31391492 | 0.81 | NPSR1 (0.47) | NPSR1MPOACHEKDM4EALDH1A1 | |
| SCHEMBL14819968 | 0.81 | DHFR (0.52) | NPSR1MPOACHEKDM4EALDH1A1 | |
| SCHEMBL857219 | 0.81 | KDM4E (0.49) | NPSR1MPOACHEKDM4EALDH1A1 | |
| SCHEMBL30640287 | 0.81 | KDM4E (0.49) | NPSR1MPOACHEKDM4EALDH1A1 | |
| SCHEMBL24392233 | 0.78 | NPSR1 (0.44) | NPSR1MPOACHEKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009005677-A2 | ANTIVIRAL COMPOUNDS | GILEAD SCIENCES, INC. (US) | 2009-01-08 | — | — | WO | disclosed |