SCHEMBL25750063

SCHEMBL25750063

CC(C)(C)NC(=O)Nc1ccc(N)cc1

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 4/20 0.68
NPC1 O15118 2/20 0.68
MEN1 O00255 2/20 0.68
KMT2A Q03164 2/20 0.68
MAPT P10636 2/20 0.67
GAA P10253 3/20 0.53
KDM4E B2RXH2 3/20 0.53
TP53 P04637 2/20 0.53
SMN1; SMN2 Q16637 2/20 0.53
ALDH1A1 P00352 1/20 0.53
HPGD P15428 1/20 0.53
CASP1 P29466 1/20 0.53
CASP7 P55210 1/20 0.53
HSD17B10 Q99714 1/20 0.53
HTT P42858 1/20 0.53
JAK2 O60674 1/20 0.52
CA12 O43570 1/20 0.51
CA1 P00915 1/20 0.51
CA2 P00918 1/20 0.51
CA9 Q16790 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13756247 0.90 RAB9A (0.81) RAB9ANPC1MEN1KMT2AMAPT
SCHEMBL23448972 0.89 RAB9A (0.67) RAB9ANPC1MEN1KMT2AMAPT
SCHEMBL5852111 0.82 RAB9A (0.70) RAB9ANPC1MEN1KMT2AMAPT
SCHEMBL25494260 0.81 RAB9A (0.64) RAB9ANPC1MEN1KMT2AGAA
SCHEMBL8772924 0.81 RAB9A (1.00) RAB9ANPC1MEN1KMT2AMAPT
SCHEMBL27884753 0.81 MAPT (0.67) RAB9ANPC1MEN1KMT2AMAPT
SCHEMBL15946354 0.81 NPC1 (0.68) RAB9ANPC1MEN1KMT2AMAPT
SCHEMBL13234045 0.81 NPC1 (0.68) RAB9ANPC1MEN1KMT2AMAPT
SCHEMBL13141239 0.81 NPC1 (0.68) RAB9ANPC1MEN1KMT2AMAPT
SCHEMBL13377396 0.81 NPC1 (0.68) RAB9ANPC1MEN1KMT2AMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023112764-A1 RELEASE LAYER-FORMING COMPOSITION AND RELEASE LAYER 日産化学株式会社 2023-06-22 WO disclosed