SCHEMBL8772924

SCHEMBL8772924

Nc1ccc(NC(=O)Nc2ccc(N)cc2)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ RAB9A P51151 4/20 1.00
▸ MAPT P10636 2/20 1.00
▸ CA12 O43570 1/20 0.70
▸ CA1 P00915 1/20 0.70
▸ CA2 P00918 1/20 0.70
▸ CA9 Q16790 1/20 0.70
▸ KMT2A Q03164 6/20 0.64
▸ MEN1 O00255 4/20 0.64
▸ PKM P14618 2/20 0.64
▸ LMNA P02545 2/20 0.64
▸ POLB P06746 1/20 0.64
▸ APEX1 P27695 1/20 0.64
▸ TDP1 Q9NUW8 1/20 0.64
▸ EPHX1 P07099 2/20 0.58
▸ GAA P10253 1/20 0.58
▸ EPHX2 P34913 2/20 0.56
▸ SMN1; SMN2 Q16637 2/20 0.56
▸ TP53 P04637 1/20 0.56
▸ TSHR P16473 1/20 0.56
▸ CDK9 P50750 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL546369 0.91 RAB9A (0.83) RAB9AMAPTCA12CA1CA2
SCHEMBL12973530 0.89 MAPT (0.79) RAB9AMAPTCA12CA1CA2
SCHEMBL11593412 0.89 RAB9A (0.79) RAB9AMAPTCA12CA1CA2
SCHEMBL10589311 0.88 MAPT (0.78) RAB9AMAPTCA12CA1CA2
SCHEMBL3460997 0.87 MAPT (0.76) RAB9AMAPTCA12CA1CA2
SCHEMBL7883674 0.87 MAPT (0.76) RAB9AMAPTCA12CA1CA2
SCHEMBL7298885 0.86 MAPT (0.75) RAB9AMAPTCA12CA1CA2
SCHEMBL12973545 0.84 EPHX2 (0.81) RAB9AMAPTCA12CA1CA2
SCHEMBL11895730 0.84 RAB9A (0.81) RAB9AMAPTCA12CA1CA2
SCHEMBL28624169 0.84 MAPT (0.70) RAB9AMAPTCA12CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 120 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119569979-B Ureido covalent organic framework material, preparation method and application thereof 北京理工大学 2025-05-30 — — CN claimed
CN-116814278-B Liquid crystal aligning agent, liquid crystal alignment film prepared by using the same and display element containing the alignment film 合肥中聚和成电子材料有限公司 2025-05-16 — — CN claimed
CN-119569979-A Ureido covalent organic framework material, preparation method and application thereof 北京理工大学 2025-03-07 — — CN claimed
CN-116814278-A Liquid crystal aligning agent, liquid crystal alignment film prepared by using the same and display element containing the alignment film 合肥中聚和成电子材料有限公司 2023-09-29 — — CN claimed
CN-110734771-B Liquid crystal aligning agent, liquid crystal alignment film and liquid crystal display element 江苏三月科技股份有限公司 2022-12-20 — — CN claimed
US-11453826-B2 Liquid crystal alignment agent, liquid crystal alignment film and liquid crystal display element JIANGSU SUNERA TECHNOLOGY CO., LTD. (CN) 2022-09-27 — — US claimed
CN-112175636-B Liquid crystal orientation agent and application thereof 波米科技有限公司 2022-09-06 — — CN claimed
US-20220204854-A1 LIQUID CRYSTAL ALIGNMENT AGENT, LIQUID CRYSTAL ALIGNMENT FILM AND LIQUID CRYSTAL DISPLAY ELEMENT JIANGSU SUNERA TECHNOLOGY CO., LTD. (CN) 2022-06-30 — — US claimed
CN-111215148-B ZIF @ TU-POP composite catalyst and preparation method and application thereof 辽宁大学 2022-06-14 — — CN claimed
WO-2021056971-A1 LIQUID CRYSTAL ALIGNMENT AGENT, LIQUID CRYSTAL ALIGNMENT FILM AND LIQUID CRYSTAL DISPLAY ELEMENT 江苏三月光电科技有限公司 2021-04-01 — — WO claimed
CN-122079830-A 1- (4-Aminophenyl) -3- [ (4-aminophenyl) carbamoylamino ] urea and preparation method and application thereof — 2026-05-26 — — CN disclosed
CN-122029478-A Liquid crystal aligning agent, liquid crystal alignment film and liquid crystal display element 日产化学株式会社 2026-05-12 — — CN disclosed
US-20250257265-A1 LIQUID CRYSTAL ALIGNING AGENT, LIQUID CRYSTAL ALIGNMENT FILM AND LIQUID CRYSTAL DISPLAY ELEMENT NISSAN CHEMICAL CORPORATION (JP) 2025-08-14 — — US disclosed
US-20250214964-A1 COMPOUNDS DERIVED FROM 4-AMINO-N-(4-AMINOPHENYL) BENZAMIDE AND ANALOGUES AND USE THEREOF CONSEJO SUPERIOR DE INVESTIGACIONES CIENTIFICAS (ES) 2025-07-03 — — US disclosed
WO-2025127092-A1 LIQUID CRYSTAL ALIGNMENT AGENT, LIQUID CRYSTAL ALIGNMENT FILM, AND LIQUID CRYSTAL DISPLAY ELEMENT 日産化学株式会社 2025-06-19 — — WO disclosed
US-4035344-A Process for preparing ordered aromatic copolyamide urea polymer THE FIRESTONE TIRE & RUBBER COMPANY (US) 1977-07-12 — — US disclosed
US-3996282-A Water-soluble quaternary ammonium dyestuffs STERLING DRUG INC. (US) 1976-12-07 — — US disclosed
US-3992143-A DISAZO AND TRIAZO DYESTUFFS BAYER AKTIENGESELLSCHAFT (DT) 1976-11-16 — — US disclosed
US-3987022-A YELLOW TO ORANGE DISAZO CATIONIC DYES CONTAINING TWO HETEROCYCLIC QUATERNARY AMMONIUM GROUPS E. I. DU PONT DE NEMOURS AND COMPANY (US) 1976-10-19 — — US disclosed
US-3960818-A Ordered aromatic copolyamide urea polymer THE FIRESTONE TIRE & RUBBER COMPANY (US) 1976-06-01 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250214964-A1 COMPOUNDS DERIVED FROM 4-AMINO-N-(4-AMINOPHENYL) BENZAMIDE AND ANALOGUES AND USE THEREOF ABAT, AADAT, AADAC RAB9A 1234/4885MAPT 3378/4885CA12 4311/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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