SCHEMBL25751079

SCHEMBL25751079

Cc1ccc(Oc2ccc(C(c3ccc(Oc4ccc(N5C(=O)C6C7CCC(C8C(=O)N(C)C(=O)C78)C6C5=O)cc4)cc3)(C(F)(F)F)C(F)(F)F)cc2)cc1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
TP53 P04637 1/20 0.38
GAA P10253 1/20 0.35
FFAR1 O14842 1/20 0.35
NPBWR1 P48145 1/20 0.35
MCHR1 Q99705 1/20 0.35
CACNA1B Q00975 1/20 0.34
APBA1 Q02410 1/20 0.34
MEN1 O00255 3/20 0.33
KMT2A Q03164 3/20 0.33
KDM4E B2RXH2 2/20 0.33
ALDH1A1 P00352 2/20 0.33
MAPT P10636 2/20 0.33
HPGD P15428 1/20 0.33
HIF1A Q16665 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
LIPE Q05469 2/20 0.33
ADCY2 Q08462 1/20 0.32
USP2 O75604 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13400440 0.89 LMNA (0.48) LMNASMN1; SMN2TP53GAAFFAR1
SCHEMBL13855428 0.85 LMNA (0.46) LMNASMN1; SMN2TP53GAAFFAR1
SCHEMBL12084645 0.85 TP53 (0.44) LMNASMN1; SMN2TP53GAACACNA1B
SCHEMBL12589254 0.81 SMN1; SMN2 (0.42) LMNASMN1; SMN2TP53GAACACNA1B
SCHEMBL12539789 0.79 TP53 (0.49) LMNASMN1; SMN2TP53GAACACNA1B
SCHEMBL13773285 0.79 TP53 (0.42) LMNASMN1; SMN2TP53GAACACNA1B
SCHEMBL14208340 0.79 SMN1; SMN2 (0.46) LMNASMN1; SMN2TP53GAACACNA1B
SCHEMBL25751300 0.78 MAPT (0.30) TP53MCHR1ALDH1A1MAPTHPGD
SCHEMBL25751305 0.78 NPC1 (0.39) MCHR1CACNA1BAPBA1KMT2AMAPT
SCHEMBL12137897 0.77 TP53 (0.47) LMNASMN1; SMN2TP53GAACACNA1B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230205031-A1 ELECTROCHROMIC COMPOSITION, ELECTROCHROMIC LAYER AND ELECTROCHROMIC DEVICE INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) 2023-06-29 US disclosed