SCHEMBL13855428

SCHEMBL13855428

Cc1ccc(Oc2ccc(-c3ccc(Oc4ccc(N5C(=O)C6C7CCC(C8C(=O)N(C)C(=O)C78)C6C5=O)cc4)cc3)cc2)cc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.46
SMN1; SMN2 Q16637 2/20 0.46
TP53 P04637 1/20 0.44
GAA P10253 1/20 0.40
MEN1 O00255 3/20 0.37
KMT2A Q03164 3/20 0.37
FFAR1 O14842 1/20 0.37
ALDH1A1 P00352 3/20 0.37
MAPT P10636 3/20 0.37
KDM4E B2RXH2 2/20 0.37
CACNA1B Q00975 1/20 0.37
APBA1 Q02410 1/20 0.37
HPGD P15428 1/20 0.37
HIF1A Q16665 1/20 0.37
TDP1 Q9NUW8 1/20 0.37
ADCY2 Q08462 1/20 0.36
F2 P00734 1/20 0.36
ELANE P08246 1/20 0.36
CTSG P08311 1/20 0.36
CMA1 P23946 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13400440 0.96 LMNA (0.48) LMNASMN1; SMN2TP53GAAMEN1
SCHEMBL13855427 0.91 TP53 (0.46) LMNASMN1; SMN2TP53GAAMEN1
SCHEMBL12539789 0.86 TP53 (0.49) LMNASMN1; SMN2TP53GAAMEN1
SCHEMBL14208340 0.86 SMN1; SMN2 (0.46) LMNASMN1; SMN2TP53GAAMEN1
SCHEMBL25751079 0.85 LMNA (0.40) LMNASMN1; SMN2TP53GAAMEN1
SCHEMBL13855426 0.85 TP53 (0.44) LMNASMN1; SMN2TP53GAAMEN1
SCHEMBL12799504 0.84 TP53 (0.47) LMNASMN1; SMN2TP53GAAMEN1
SCHEMBL12137897 0.84 TP53 (0.47) LMNASMN1; SMN2TP53GAAMEN1
SCHEMBL16405696 0.82 TP53 (0.53) LMNASMN1; SMN2TP53GAAMEN1
SCHEMBL13624488 0.82 LMNA (0.46) LMNASMN1; SMN2TP53MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230205031-A1 ELECTROCHROMIC COMPOSITION, ELECTROCHROMIC LAYER AND ELECTROCHROMIC DEVICE INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) 2023-06-29 US disclosed
US-20090136689-A1 LIQUID CRYSTAL DISPLAY DEVICE LEU CHYI-MING 2009-05-28 US disclosed
US-20070065603-A1 Liquid crystal display device INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE 2007-03-22 US disclosed