Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CLK4 | Q9HAZ1 | 5/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | CLK1 | P49759 | 1/20 | 0.47 |
| ▸ | VNN1 | O95497 | 1/20 | 0.46 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.45 |
| ▸ | PRUNE1 | Q86TP1 | 1/20 | 0.44 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2600008 | 0.82 | CLK4 (0.50) | CLK4NPC1RAB9AMAPTKMT2A | |
| SCHEMBL25751247 | 0.80 | VNN1 (0.49) | CLK4NPC1RAB9AMAPTKMT2A | |
| SCHEMBL501215 | 0.77 | DYRK1A (0.52) | CLK4NPC1RAB9AMAPTCLK1 | |
| SCHEMBL25382508 | 0.76 | CLK4 (0.44) | CLK4NPC1RAB9AMAPTKMT2A | |
| SCHEMBL2563374 | 0.76 | CLK4 (0.52) | CLK4NPC1RAB9AMAPTKMT2A | |
| SCHEMBL2600009 | 0.75 | CLK4 (0.55) | CLK4NPC1RAB9AMAPTKMT2A | |
| SCHEMBL16864627 | 0.75 | KDM4E (0.53) | CLK4NPC1RAB9AMAPTKMT2A | |
| SCHEMBL2564636 | 0.75 | CLK4 (0.48) | CLK4NPC1RAB9AMAPTKMT2A | |
| SCHEMBL501471 | 0.75 | PTGDR (0.46) | CLK4NPC1RAB9AMAPTCLK1 | |
| SCHEMBL21384146 | 0.74 | RAB9A (0.63) | CLK4NPC1RAB9AMAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023109954-A1 | TYK2 INHIBITORS AND COMPOSITIONS AND METHODS THEREOF | LYNK PHARMACEUTICALS CO. LTD. (CN) | 2023-06-22 | — | — | WO | disclosed |