SCHEMBL2575165

SCHEMBL2575165

OC[C@H]1O[C@@H](Oc2ccccc2Cc2ccccc2)[C@H](O)[C@@H](O)[C@@H]1O

nearest known ligand 0.81

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ SLC5A2 P31639 17/20 0.81
▸ SLC5A1 P13866 13/20 0.78

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1037900 1.00 SLC5A2 (0.81) SLC5A2SLC5A1
SCHEMBL10822009 0.99 SLC5A2 (0.79) SLC5A2SLC5A1
SCHEMBL2583297 0.91 SLC5A2 (0.80) SLC5A2SLC5A1
SCHEMBL2576286 0.91 SLC5A2 (0.80) SLC5A2SLC5A1
SCHEMBL4356542 0.90 SLC5A2 (0.82) SLC5A2SLC5A1
SCHEMBL2582707 0.90 SLC5A2 (0.78) SLC5A2SLC5A1
SCHEMBL2577417 0.90 SLC5A2 (0.78) SLC5A2SLC5A1
SCHEMBL4350700 0.90 SLC5A2 (1.00) SLC5A2SLC5A1
SCHEMBL2577336 0.90 SLC5A2 (1.00) SLC5A2SLC5A1
SCHEMBL2578932 0.90 SLC5A2 (0.78) SLC5A2SLC5A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8048897-B2 Cyclohexane derivative, prodrug thereof and salt thereof, and therapeutic agent containing the same for diabetes CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2011-11-01 — — US claimed
US-20080318874-A1 Novel Cyclohexane Derivative, Prodrug Thereof and Salt Thereof, and Therapeutic Agent Containing the Same for Diabetes CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2008-12-25 — — US claimed
EP-1783110-A1 NOVEL CYCLOHEXANE DERIVATIVE, PRODRUG THEREOF AND SALT THEREOF, AND THERAPEUTIC AGENT CONTAINING THE SAME FOR DIABETES CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2007-05-09 — — EP claimed
US-8048897-B2 Cyclohexane derivative, prodrug thereof and salt thereof, and therapeutic agent containing the same for diabetes CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2011-11-01 — — US disclosed
US-20110059910-A1 Novel aromatic fluoroglycoside derivatives, pharmaceuticals comprising said compounds and the use thereof SANOFI-AVENTIS (FR) 2011-03-10 — — US disclosed
US-7820804-B2 Fluoroglycoside derivatives of pyrazoles, medicaments containing these compounds, and the use thereof Sanofi-Aventia Deutschland GmbH (DE) 2010-10-26 — — US disclosed
US-20100261664-A1 Novel heterocyclic fluoroglycoside derivatives, medicaments containing these compounds, and the use thereof SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) 2010-10-14 — — US disclosed
US-20080318874-A1 Novel Cyclohexane Derivative, Prodrug Thereof and Salt Thereof, and Therapeutic Agent Containing the Same for Diabetes CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2008-12-25 — — US disclosed
US-20070197623-A1 NOVEL FLUOROGLYCOSIDE DERIVATIVES OF PYRAZOLES, MEDICAMENTS CONTAINING THESE COMPOUNDS, AND THE USE THEREOF SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) 2007-08-23 — — US disclosed
EP-1783110-A1 NOVEL CYCLOHEXANE DERIVATIVE, PRODRUG THEREOF AND SALT THEREOF, AND THERAPEUTIC AGENT CONTAINING THE SAME FOR DIABETES CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2007-05-09 — — EP disclosed
US-20040259819-A1 Novel heterocyclic fluoroglycoside derivatives, medicaments containing these compounds, and the use thereof AVENTIS PHARMA DEUTSCHLAND GMBH (DE) 2004-12-23 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100261664-A1 Novel heterocyclic fluoroglycoside derivatives, medicaments containing these compounds, and the use thereof UGGT1, SLC5A2, SLC5A1 SLC5A2 2/4885SLC5A1 3/4885
US-20080318874-A1 Novel Cyclohexane Derivative, Prodrug Thereof and Salt Thereof, and Therapeutic Agent Containing the Same for Diabetes SLC5A1, GPR119, SLC5A2 SLC5A2 3/4885SLC5A1 1/4885
US-20110059910-A1 Novel aromatic fluoroglycoside derivatives, pharmaceuticals comprising said compounds and the use thereof SLC5A2, SLC5A1, SLC2A2 SLC5A2 1/4885SLC5A1 2/4885
US-20040259819-A1 Novel heterocyclic fluoroglycoside derivatives, medicaments containing these compounds, and the use thereof SLC5A1, UGGT1, SLC5A2 SLC5A2 3/4885SLC5A1 1/4885
US-20070197623-A1 NOVEL FLUOROGLYCOSIDE DERIVATIVES OF PYRAZOLES, MEDICAMENTS CONTAINING THESE COMPOUNDS, AND THE USE THEREOF DPP4, UGGT1, SLC5A2 SLC5A2 3/4885SLC5A1 4/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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