⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25752107 | 0.90 | TYMS (0.31) | — | |
| SCHEMBL25751493 | 0.90 | TYMS (0.31) | — | |
| SCHEMBL25752104 | 0.82 | TK1 (0.41) | — | |
| SCHEMBL25751491 | 0.78 | — | — | |
| SCHEMBL25751535 | 0.76 | TK1 (0.52) | — | |
| SCHEMBL25751494 | 0.76 | TK1 (0.52) | — | |
| SCHEMBL25751490 | 0.70 | — | — | |
| SCHEMBL26420465 | 0.69 | POLA1 (0.34) | — | |
| SCHEMBL16158115 | 0.69 | TK1 (0.36) | — | |
| SCHEMBL25752106 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230203484-A1 | DOUBLE STRANDED OLIGONUCLEOTIDE COMPOSITIONS AND METHODS RELATING THERETO | WAVE LIFE SCIENCES LTD. (SG) | 2023-06-29 | — | — | US | disclosed |