Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR1 | P11362 | 20/20 | 0.68 |
| ▸ | FGFR2 | P21802 | 20/20 | 0.68 |
| ▸ | FGFR3 | P22607 | 20/20 | 0.68 |
| ▸ | FGFR4 | P22455 | 19/20 | 0.68 |
| ▸ | KDR | P35968 | 17/20 | 0.68 |
| ▸ | FLT3 | P36888 | 9/20 | 0.67 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.60 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.60 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.60 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.60 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.60 |
| ▸ | DRD3 | P35462 | 1/20 | 0.60 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.60 |
| ▸ | ETV6 | P41212 | 1/20 | 0.60 |
| ▸ | HTR2B | P41595 | 1/20 | 0.60 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.60 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18675934 | 0.93 | FGFR1 (0.77) | FGFR1FGFR2FGFR3FGFR4KDR | |
| SCHEMBL14906703 | 0.88 | FGFR1 (0.78) | FGFR1FGFR2FGFR3FGFR4KDR | |
| SCHEMBL16132959 | 0.85 | FGFR1 (0.75) | FGFR1FGFR2FGFR3FGFR4KDR | |
| SCHEMBL14906768 | 0.83 | FGFR3 (0.75) | FGFR1FGFR2FGFR3FGFR4KDR | |
| SCHEMBL14906810 | 0.83 | FGFR1 (0.66) | FGFR1FGFR2FGFR3FGFR4KDR | |
| SCHEMBL14906705 | 0.82 | FGFR1 (0.69) | FGFR1FGFR2FGFR3FGFR4KDR | |
| SCHEMBL21946934 | 0.81 | FGFR1 (0.80) | FGFR1FGFR2FGFR3FGFR4KDR | |
| SCHEMBL12178368 | 0.81 | FGFR1 (1.00) | FGFR1FGFR2FGFR3FGFR4KDR | |
| SCHEMBL18675926 | 0.80 | FGFR3 (0.75) | FGFR1FGFR2FGFR3FGFR4KDR | |
| SCHEMBL14906756 | 0.80 | FGFR3 (0.75) | FGFR1FGFR2FGFR3FGFR4KDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230203011-A1 | BI-Heteroaryl Substitute 1,4-Benzodiazepines And Uses Thereof For The Treatment Of Cancer | JANSSEN PHARMACEUTICA NV (BE) | 2023-06-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230203011-A1 | BI-Heteroaryl Substitute 1,4-Benzodiazepines And Uses Thereof For The Treatment Of Cancer | GABBR1, GABRA5, GABRA4 | FGFR1 2124/4885FGFR2 1594/4885FGFR3 1030/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.