Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TK1 | P04183 | 6/20 | 0.44 |
| ▸ | TOP2A | P11388 | 4/20 | 0.44 |
| ▸ | RNASE1 | P07998 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | DHFR | P00374 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24059078 | 0.92 | TK1 (0.45) | TK1TOP2ARNASE1POLB | |
| SCHEMBL24059155 | 0.88 | TK1 (0.45) | TK1TOP2ARNASE1POLB | |
| SCHEMBL23270835 | 0.87 | TOP2A (0.51) | TK1TOP2ARNASE1DHFR | |
| SCHEMBL12942602 | 0.87 | TOP2A (0.51) | TK1TOP2ARNASE1DHFR | |
| SCHEMBL24059076 | 0.87 | TOP2A (0.51) | TK1TOP2ARNASE1DHFR | |
| SCHEMBL25971927 | 0.87 | RNASE1 (0.46) | TK1RNASE1 | |
| SCHEMBL6830804 | 0.85 | TOP2A (0.49) | TK1TOP2ARNASE1DHFR | |
| SCHEMBL6830807 | 0.85 | TOP2A (0.49) | TK1TOP2ARNASE1DHFR | |
| SCHEMBL8904506 | 0.85 | TK1 (0.47) | TK1TOP2ARNASE1DHFR | |
| SCHEMBL8904501 | 0.85 | TK1 (0.47) | TK1TOP2ARNASE1DHFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230203484-A1 | DOUBLE STRANDED OLIGONUCLEOTIDE COMPOSITIONS AND METHODS RELATING THERETO | WAVE LIFE SCIENCES LTD. (SG) | 2023-06-29 | — | — | US | disclosed |