Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TK1 | P04183 | 7/20 | 0.45 |
| ▸ | TOP2A | P11388 | 4/20 | 0.42 |
| ▸ | NT5M | Q9NPB1 | 1/20 | 0.40 |
| ▸ | RNASE1 | P07998 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25757560 | 0.92 | TK1 (0.46) | TK1TOP2ANT5MRNASE1POLB | |
| SCHEMBL25752294 | 0.92 | TK1 (0.45) | TK1TOP2ANT5MRNASE1POLB | |
| SCHEMBL25757642 | 0.86 | TK1 (0.46) | TK1TOP2ARNASE1POLB | |
| SCHEMBL25752289 | 0.84 | TK1 (0.59) | TK1POLB | |
| SCHEMBL24233273 | 0.83 | TK1 (0.50) | TK1TOP2ARNASE1 | |
| SCHEMBL22020924 | 0.83 | TK1 (0.50) | TK1TOP2ARNASE1 | |
| SCHEMBL24059205 | 0.83 | TK1 (0.50) | TK1TOP2ARNASE1 | |
| SCHEMBL4580652 | 0.83 | TK1 (0.50) | TK1TOP2ARNASE1 | |
| SCHEMBL4580654 | 0.83 | TK1 (0.50) | TK1TOP2ARNASE1 | |
| SCHEMBL22314627 | 0.82 | TK1 (0.51) | TK1TOP2ARNASE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230203484-A1 | DOUBLE STRANDED OLIGONUCLEOTIDE COMPOSITIONS AND METHODS RELATING THERETO | WAVE LIFE SCIENCES LTD. (SG) | 2023-06-29 | — | — | US | disclosed |