SCHEMBL25752485

SCHEMBL25752485

CC(C)c1ccc2c(=O)c3cc4c(cc3n(-c3c(C(C)(C)C)cc(C(C)(C)C)cc3C(C)(C)C)c2c1)c(=O)c1ccc(C(C)(C)C)cc1n4-c1c(C(C)(C)C)cc(C(C)(C)C)cc1C(C)(C)C

nearest known ligand 0.33

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PPARG P37231 1/20 0.33
CYP2D6 P10635 1/20 0.30
CYP2C9 P11712 1/20 0.30
HIF1A Q16665 1/20 0.30
TBK1 Q9UHD2 1/20 0.30
NPC1 O15118 1/20 0.30
ALDH1A1 P00352 1/20 0.30
PLA2G1B P04054 1/20 0.30
NFKB1 P19838 1/20 0.30
CASP3 P42574 1/20 0.30
RAB9A P51151 1/20 0.30
NFKB2 Q00653 1/20 0.30
RELA Q04206 1/20 0.30
SENP8 Q96LD8 1/20 0.30
SENP7 Q9BQF6 1/20 0.30
SENP6 Q9GZR1 1/20 0.30
L3MBTL1 Q9Y468 1/20 0.30
ATG4B Q9Y4P1 1/20 0.30
BCL2 P10415 1/20 0.30
MCL1 Q07820 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25752489 0.96 PPARG (0.33) PPARGTBK1
SCHEMBL25752563 0.87 PPARG (0.33) PPARG
SCHEMBL25824818 0.86 PGR (0.35) NPC1ALDH1A1PLA2G1BNFKB1CASP3
SCHEMBL25752570 0.85 NR1I2 (0.34)
SCHEMBL25752473 0.82 PPARG (0.32) PPARGNPC1ALDH1A1PLA2G1BNFKB1
SCHEMBL25752400 0.82 PPARG (0.44) PPARGTBK1ALDH1A1L3MBTL1BCL2
SCHEMBL25752387 0.82 PPARG (0.41) PPARGCYP2D6CYP2C9HIF1ANPC1
SCHEMBL25752447 0.82 PPARG (0.35) PPARGTBK1L3MBTL1
SCHEMBL25752422 0.80 PPARG (0.35) PPARGNPC1ALDH1A1PLA2G1BNFKB1
SCHEMBL25752483 0.79 MARK4 (0.33) BCL2MCL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230209987-A1 ORGANIC LIGHT EMITTING DIODE AND ORGANIC LIGHT EMITTING DISPLAY DEVICE HAVING THE SAME LG DISPLAY CO., LTD. (KR) 2023-06-29 US disclosed
US-20230209987-A1 ORGANIC LIGHT EMITTING DIODE AND ORGANIC LIGHT EMITTING DISPLAY DEVICE HAVING THE SAME LG DISPLAY CO., LTD. (KR) 2023-06-29 US disclosed
US-20230209988-A1 ORGANIC LIGHT EMITTING DIODE AND ORGANIC LIGHT EMITTING DISPLAY DEVICE HAVING THE SAME LG DISPLAY CO., LTD. (KR) 2023-06-29 US disclosed
US-20230209988-A1 ORGANIC LIGHT EMITTING DIODE AND ORGANIC LIGHT EMITTING DISPLAY DEVICE HAVING THE SAME LG DISPLAY CO., LTD. (KR) 2023-06-29 US disclosed