SCHEMBL25752400

SCHEMBL25752400

CC(C)c1ccc2c(=O)c3cc4c(cc3n(-c3ccc(C(C)(C)C)cc3)c2c1)c(=O)c1ccc(C(C)C)cc1n4-c1ccc(C(C)(C)C)cc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PPARG P37231 2/20 0.44
NR1H4 Q96RI1 2/20 0.35
MAT2A P31153 1/20 0.35
USP14 P54578 1/20 0.34
MAPK8 P45983 1/20 0.34
TDP1 Q9NUW8 1/20 0.34
ALDH1A1 P00352 2/20 0.33
PTGES2 Q9H7Z7 1/20 0.33
KDM4E B2RXH2 1/20 0.33
BCL2 P10415 1/20 0.33
MCL1 Q07820 1/20 0.33
MGLL Q99685 1/20 0.33
MAPT P10636 1/20 0.33
MAPK1 P28482 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33
PTGES O14684 1/20 0.33
CASR P41180 1/20 0.33
PMM2 O15305 1/20 0.33
MPI P34949 1/20 0.33
PHOSPHO1 Q8TCT1 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25752387 0.92 PPARG (0.41) PPARGNR1H4MAT2AMAPK8TDP1
SCHEMBL25752447 0.89 PPARG (0.35) PPARGMAT2AUSP14MGLLL3MBTL1
SCHEMBL25752390 0.89 MGLL (0.42) PPARGMAT2AUSP14MAPK8TDP1
SCHEMBL25752397 0.86 NR1H4 (0.40) PPARGNR1H4MAT2AMAPK8ALDH1A1
SCHEMBL25752378 0.85 TDP1 (0.39) MAT2AUSP14MAPK8TDP1ALDH1A1
SCHEMBL25752422 0.84 PPARG (0.35) PPARGMAT2AMAPK8ALDH1A1MAPT
SCHEMBL25752399 0.83 NR1H4 (0.37) PPARGNR1H4ALDH1A1MAPTMAPK1
SCHEMBL25752365 0.83 MAT2A (0.50) MAT2AMAPK8ALDH1A1KDM4EMAPK1
SCHEMBL25752394 0.82 NR1H4 (0.40) PPARGNR1H4MAPK8ALDH1A1BCL2
SCHEMBL25752433 0.81 MAT2A (0.36) MAT2AUSP14MAPK8TDP1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230209987-A1 ORGANIC LIGHT EMITTING DIODE AND ORGANIC LIGHT EMITTING DISPLAY DEVICE HAVING THE SAME LG DISPLAY CO., LTD. (KR) 2023-06-29 US disclosed
US-20230209987-A1 ORGANIC LIGHT EMITTING DIODE AND ORGANIC LIGHT EMITTING DISPLAY DEVICE HAVING THE SAME LG DISPLAY CO., LTD. (KR) 2023-06-29 US disclosed
US-20230209988-A1 ORGANIC LIGHT EMITTING DIODE AND ORGANIC LIGHT EMITTING DISPLAY DEVICE HAVING THE SAME LG DISPLAY CO., LTD. (KR) 2023-06-29 US disclosed
US-20230209988-A1 ORGANIC LIGHT EMITTING DIODE AND ORGANIC LIGHT EMITTING DISPLAY DEVICE HAVING THE SAME LG DISPLAY CO., LTD. (KR) 2023-06-29 US disclosed