Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | CCNC | P24863 | 4/20 | 0.36 |
| ▸ | CDK8 | P49336 | 4/20 | 0.36 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | THPO | P40225 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.31 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.30 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.30 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25752574 | 0.83 | SIRT3 (0.41) | SIRT3TDP1CCNCCDK8TRPA1 | |
| SCHEMBL14822507 | 0.81 | TRPA1 (0.35) | SIRT3TDP1CCNCCDK8TRPA1 | |
| SCHEMBL21881933 | 0.81 | TRPA1 (0.35) | SIRT3TDP1CCNCCDK8TRPA1 | |
| SCHEMBL9000344 | 0.78 | TRPA1 (0.33) | SIRT3TDP1CCNCCDK8TRPA1 | |
| SCHEMBL9756927 | 0.77 | CCNC (0.50) | SIRT3TDP1CCNCCDK8TSHR | |
| SCHEMBL9756928 | 0.77 | CCNC (0.50) | SIRT3TDP1CCNCCDK8TSHR | |
| SCHEMBL21707400 | 0.76 | CYP2A6 (0.33) | SIRT3TDP1CCNCCDK8TRPA1 | |
| SCHEMBL27251623 | 0.76 | TRPA1 (0.33) | SIRT3TDP1CCNCCDK8TRPA1 | |
| SCHEMBL18630229 | 0.76 | TRPA1 (0.33) | SIRT3TDP1CCNCCDK8TRPA1 | |
| SCHEMBL26508276 | 0.76 | SIRT3 (0.35) | SIRT3TDP1CCNCCDK8TRPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230197361-A1 | CONDUCTIVE TWO-DIMENSIONAL (2D) COVALENT ORGANIC FRAMEWORKS (COFS) AND METHOD OF MAKING AN ELECTRODE MATERIAL | UNIV KING ABDULLAH SCI & TECH (SA) | 2023-06-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230197361-A1 | CONDUCTIVE TWO-DIMENSIONAL (2D) COVALENT ORGANIC FRAMEWORKS (COFS) AND METHOD OF MAKING AN ELECTRODE MATERIAL | TET3, TET1, ALKBH2 | SIRT3 940/4885TDP1 2631/4885CCNC 532/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.