SCHEMBL25752702

SCHEMBL25752702

CC[C@H]1O[C@@H](n2cnc3c(On4nnc5ccccc54)ncnc32)CC1ON=C(C)C

nearest known ligand 0.39

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
HIF1A Q16665 1/20 0.39
SLC29A1 Q99808 2/20 0.33
SMN1; SMN2 Q16637 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21011207 0.90 HIF1A (0.36) HIF1ASLC29A1
SCHEMBL13239710 0.86 HIF1A (0.48) HIF1A
SCHEMBL13239659 0.85 HIF1A (0.39) HIF1ASLC29A1
SCHEMBL13239719 0.85 HIF1A (0.35) HIF1ASLC29A1
SCHEMBL26647666 0.81 HIF1A (0.56) HIF1ASLC29A1SMN1; SMN2
SCHEMBL15171798 0.81 HIF1A (0.56) HIF1ASLC29A1SMN1; SMN2
SCHEMBL30609212 0.81 HIF1A (0.56) HIF1ASLC29A1SMN1; SMN2
SCHEMBL13239667 0.81 HIF1A (0.56) HIF1ASLC29A1SMN1; SMN2
SCHEMBL13265482 0.80 HIF1A (0.42) HIF1ASLC29A1
SCHEMBL13239711 0.79 HIF1A (0.30) HIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230175030-A1 NUCLEIC ACID POLYMER WITH AMINE-MASKED BASES Nuclera Nucleics Ltd. (GB) 2023-06-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230175030-A1 NUCLEIC ACID POLYMER WITH AMINE-MASKED BASES RNGTT, POLM, POLRMT HIF1A 2566/4885SLC29A1 850/4885SMN1; SMN2 747/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.