SCHEMBL25752734

SCHEMBL25752734

COC(=O)CNC(=O)C(=O)[C@@H]1CCCN1C(=O)CNC(=O)c1ccnc2ccccc12

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
FAP Q12884 20/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30169842 1.00 FAP (1.00) FAP
SCHEMBL26348944 1.00 FAP (1.00) FAP
SCHEMBL26349148 0.97 FAP (1.00) FAP
SCHEMBL30169765 0.92 FAP (1.00) FAP
SCHEMBL25752735 0.92 FAP (1.00) FAP
SCHEMBL26348966 0.92 FAP (1.00) FAP
SCHEMBL30169843 0.90 FAP (0.85) FAP
SCHEMBL30414389 0.89 FAP (0.85) FAP
SCHEMBL25239559 0.89 FAP (1.00) FAP
SCHEMBL25283860 0.89 FAP (1.00) FAP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230192647-A1 COMPOUNDS FOR INHIBITION OF FIBROBLAST ACTIVATION PROTEIN USTAV ORGANICKE CHEMIE A BIOCHEMIE AV CR, V. V. I. (CZ) 2023-06-22 US disclosed
US-20230192647-A1 COMPOUNDS FOR INHIBITION OF FIBROBLAST ACTIVATION PROTEIN USTAV ORGANICKE CHEMIE A BIOCHEMIE AV CR, V. V. I. (CZ) 2023-06-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230192647-A1 COMPOUNDS FOR INHIBITION OF FIBROBLAST ACTIVATION PROTEIN FAP, FIBP, APC FAP 1/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.