Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 1/20 | 0.58 |
| ▸ | FNTA | P49354 | 6/20 | 0.57 |
| ▸ | FNTB | P49356 | 4/20 | 0.57 |
| ▸ | PGGT1B | P53609 | 3/20 | 0.55 |
| ▸ | TRPV1 | Q8NER1 | 6/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2574551 | 1.00 | TRPA1 (0.58) | TRPA1FNTAFNTBPGGT1BTRPV1 | |
| SCHEMBL2574549 | 1.00 | TRPA1 (0.58) | TRPA1FNTAFNTBPGGT1BTRPV1 | |
| SCHEMBL2568549 | 0.93 | TRPA1 (0.65) | TRPA1FNTAFNTBPGGT1BTRPV1 | |
| SCHEMBL2568553 | 0.93 | TRPA1 (0.65) | TRPA1FNTAFNTBPGGT1BTRPV1 | |
| SCHEMBL2571319 | 0.93 | TRPA1 (0.65) | TRPA1FNTAFNTBPGGT1BTRPV1 | |
| SCHEMBL12164450 | 0.86 | TRPA1 (0.58) | TRPA1FNTAFNTBPGGT1BTRPV1 | |
| SCHEMBL1724109 | 0.86 | TRPA1 (0.61) | TRPA1FNTAFNTBPGGT1BTRPV1 | |
| SCHEMBL1724107 | 0.86 | TRPA1 (0.61) | TRPA1FNTAFNTBPGGT1BTRPV1 | |
| SCHEMBL12164584 | 0.85 | TRPA1 (0.54) | TRPA1FNTAFNTBPGGT1BTRPV1 | |
| SCHEMBL10051892 | 0.83 | FNTA (0.37) | TRPA1FNTAFNTBPGGT1BTRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8273398-B2 | Geranylamine derivates of oxalic acid | SYMRISE AG (DE) | 2012-09-25 | — | — | US | disclosed |
| US-8273398-B2 | Geranylamine derivates of oxalic acid | SYMRISE AG (DE) | 2012-09-25 | — | — | US | disclosed |
| US-8273398-B2 | Geranylamine derivates of oxalic acid | SYMRISE AG (DE) | 2012-09-25 | — | — | US | disclosed |
| EP-2168442-B1 | Geranylamine derivatives of oxalic acid | SYMRISE AG (DE) | 2011-11-09 | — | — | EP | disclosed |
| EP-2168442-B1 | Geranylamine derivatives of oxalic acid | SYMRISE AG (DE) | 2011-11-09 | — | — | EP | disclosed |
| US-20100080880-A1 | GERANYLAMINE DERIVATES OF OXALIC ACID | SYMRISE GMBH & CO. KG (DE) | 2010-04-01 | — | — | US | disclosed |
| US-20100080880-A1 | GERANYLAMINE DERIVATES OF OXALIC ACID | SYMRISE GMBH & CO. KG (DE) | 2010-04-01 | — | — | US | disclosed |
| US-20100080880-A1 | GERANYLAMINE DERIVATES OF OXALIC ACID | SYMRISE GMBH & CO. KG (DE) | 2010-04-01 | — | — | US | disclosed |
| EP-2168442-A2 | Geranylamine derivatives of oxalic acid | Symrise GmbH & Co. KG (DE) | 2010-03-31 | — | — | EP | disclosed |
| EP-2168442-A2 | Geranylamine derivatives of oxalic acid | Symrise GmbH & Co. KG (DE) | 2010-03-31 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100080880-A1 | GERANYLAMINE DERIVATES OF OXALIC ACID | OTC, OAT, ODC1 | TRPA1 863/4885FNTA 52/4885FNTB 754/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.