SCHEMBL25753281

SCHEMBL25753281

C[C@H]1CN(C)C[C@@H](CO)[C@@H]1O

nearest known ligand 0.44

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
GBA1 P04062 12/20 0.44
GAA P10253 3/20 0.36
MGAM O43451 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18975425 0.86 GBA1 (0.50) GBA1GAAMGAM
SCHEMBL19087104 0.84
SCHEMBL6631202 0.84
SCHEMBL8180629 0.80 GBA1 (0.60) GBA1GAAMGAM
SCHEMBL6433984 0.80 GBA1 (0.60) GBA1GAAMGAM
SCHEMBL8172380 0.80 GBA1 (0.60) GBA1GAAMGAM
SCHEMBL9052252 0.78 GBA1 (0.40) GBA1GAAMGAM
SCHEMBL22446600 0.78 GBA1 (0.40) GBA1GAAMGAM
SCHEMBL6635846 0.78 GBA1 (0.40) GBA1GAAMGAM
SCHEMBL20726321 0.77 GBA1 (0.39) GBA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11685912-B2 Affinity purification of glycosidase-cleaving enzymes TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2023-06-27 US disclosed