Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.57 |
| ▸ | HPGD | P15428 | 2/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | TP53 | P04637 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.57 |
| ▸ | NPC1 | O15118 | 3/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | RAB9A | P51151 | 2/20 | 0.57 |
| ▸ | BCHE | P06276 | 1/20 | 0.57 |
| ▸ | MAOB | P27338 | 3/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.55 |
| ▸ | CYP1A1 | P04798 | 3/20 | 0.55 |
| ▸ | CYP1B1 | Q16678 | 3/20 | 0.55 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.55 |
| ▸ | TFEB | P19484 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25753460 | 0.82 | MAOB (0.51) | MAPTHPGDMAPK1ALDH1A1MEN1 | |
| SCHEMBL25753449 | 0.78 | MAPT (0.57) | MAPTCYP3A4HPGDMAPK1ALDH1A1 | |
| SCHEMBL25753450 | 0.77 | F3 (0.57) | MAPTCYP3A4HPGDALDH1A1MEN1 | |
| SCHEMBL25753454 | 0.76 | MAOB (0.59) | MAPTCYP3A4HPGDALDH1A1NPC1 | |
| SCHEMBL19183205 | 0.74 | MAOB (0.76) | MAPTCYP3A4ALDH1A1TP53KMT2A | |
| SCHEMBL19183204 | 0.74 | MAOB (0.76) | MAPTCYP3A4ALDH1A1TP53KMT2A | |
| SCHEMBL25753466 | 0.74 | MAPT (0.55) | MAPTCYP3A4HPGDALDH1A1KMT2A | |
| SCHEMBL4535102 | 0.73 | AR (0.80) | MAPTCYP3A4HPGDALDH1A1MEN1 | |
| SCHEMBL1723179 | 0.73 | MAPT (1.00) | MAPTCYP3A4HPGDMAPK1ALDH1A1 | |
| SCHEMBL1723180 | 0.73 | MAPT (1.00) | MAPTCYP3A4HPGDMAPK1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230277508-A1 | USE OF COMPOUND AS CYP2E1 INHIBITOR | Shanghai Ling Xi Biotechnology Development Co., Ltd. (CN) | 2023-09-07 | — | — | US | disclosed |
| US-20230277508-A1 | USE OF COMPOUND AS CYP2E1 INHIBITOR | Shanghai Ling Xi Biotechnology Development Co., Ltd. (CN) | 2023-09-07 | — | — | US | disclosed |
| EP-4205741-A1 | USE OF COMPOUND AS CYP2E1 INHIBITOR | Shanghai Ling Xi Biotechnology Development Co., Ltd. (CN) | 2023-07-05 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230277508-A1 | USE OF COMPOUND AS CYP2E1 INHIBITOR | CYP2E1, CYP11B1, CYP27A1 | MAPT 1097/4885CYP3A4 45/4885HPGD 81/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.