Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 8/20 | 0.38 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.38 |
| ▸ | WDR5 | P61964 | 2/20 | 0.35 |
| ▸ | BACE1 | P56817 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25752820 | 1.00 | ADRB2 (0.38) | ADRB2ADRB1WDR5BACE1 | |
| SCHEMBL24036725 | 0.83 | CXCR2 (0.37) | WDR5 | |
| SCHEMBL25753588 | 0.83 | CXCR2 (0.37) | WDR5 | |
| SCHEMBL24036736 | 0.81 | TACR1 (0.34) | — | |
| SCHEMBL25753566 | 0.81 | TACR1 (0.34) | — | |
| SCHEMBL25622767 | 0.81 | TACR1 (0.34) | — | |
| SCHEMBL25752815 | 0.81 | SLC13A3 (0.35) | WDR5 | |
| SCHEMBL25753540 | 0.81 | SLC13A3 (0.35) | WDR5 | |
| SCHEMBL30388831 | 0.81 | SLC13A3 (0.35) | WDR5 | |
| SCHEMBL25622818 | 0.81 | AKR1C3 (0.35) | ADRB2WDR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230192661-A1 | 1, 4, 5, 6-TETRAHYDROPYRIMIDINE-2-AMINE DERIVATIVE | UBE CORPORATION (JP) | 2023-06-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230192661-A1 | 1, 4, 5, 6-TETRAHYDROPYRIMIDINE-2-AMINE DERIVATIVE | DHFR, DPYD, CYP2D6 | ADRB2 678/4885ADRB1 765/4885WDR5 2145/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.