Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | TNF | P01375 | 2/20 | 0.36 |
| ▸ | CTSA | P10619 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 4/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | PNP | P00491 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | SCN4A | P35499 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20154370 | 0.91 | L3MBTL1 (0.45) | L3MBTL1TNFMAPTRAB9AALDH1A1 | |
| SCHEMBL6341030 | 0.91 | L3MBTL1 (0.45) | L3MBTL1TNFMAPTRAB9AALDH1A1 | |
| SCHEMBL20154369 | 0.91 | L3MBTL1 (0.45) | L3MBTL1TNFMAPTRAB9AALDH1A1 | |
| SCHEMBL20158191 | 0.89 | HTT (0.38) | TNFMAPTRAB9AALDH1A1SLC7A5 | |
| SCHEMBL24036704 | 0.84 | L3MBTL1 (0.37) | L3MBTL1TNFMAPTRAB9AALDH1A1 | |
| SCHEMBL25752918 | 0.84 | L3MBTL1 (0.37) | L3MBTL1TNFMAPTRAB9AALDH1A1 | |
| Hydrochloric Acid SCHEMBL30389457 | 0.82 | L3MBTL1 (0.36) | L3MBTL1TNFMAPTRAB9AALDH1A1 | |
| SCHEMBL24036703 | 0.82 | MAPT (0.34) | MAPTRAB9AALDH1A1GAASLC7A5 | |
| Hydrochloric Acid SCHEMBL19067170 | 0.81 | CYP2C9 (0.40) | CTSAMEN1KMT2ASMN1; SMN2LMNA | |
| SCHEMBL25752836 | 0.80 | SLC13A3 (0.40) | L3MBTL1CTSAMAPTSMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230192661-A1 | 1, 4, 5, 6-TETRAHYDROPYRIMIDINE-2-AMINE DERIVATIVE | UBE CORPORATION (JP) | 2023-06-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230192661-A1 | 1, 4, 5, 6-TETRAHYDROPYRIMIDINE-2-AMINE DERIVATIVE | DHFR, DPYD, CYP2D6 | L3MBTL1 2036/4885TNF 4836/4885CTSA 4587/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.