⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25751681 | 0.79 | CHRM1 (0.33) | — | |
| SCHEMBL25753875 | 0.78 | — | — | |
| SCHEMBL27062244 | 0.74 | — | — | |
| SCHEMBL25751680 | 0.71 | KDM4E (0.33) | — | |
| SCHEMBL25751615 | 0.71 | L3MBTL1 (0.31) | — | |
| SCHEMBL25751678 | 0.70 | — | — | |
| SCHEMBL25751612 | 0.69 | — | — | |
| SCHEMBL25751672 | 0.68 | MEN1 (0.36) | — | |
| SCHEMBL25753912 | 0.68 | KDM4E (0.33) | — | |
| SCHEMBL25751686 | 0.68 | ALDH1A1 (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240026358-A1 | OLIGONUCLEOTIDE COMPOSITIONS AND METHODS THEREOF | WAVE LIFE SCIENCES LTD. (SG) | 2024-01-25 | — | — | US | disclosed |
| US-20230203484-A1 | DOUBLE STRANDED OLIGONUCLEOTIDE COMPOSITIONS AND METHODS RELATING THERETO | WAVE LIFE SCIENCES LTD. (SG) | 2023-06-29 | — | — | US | disclosed |
| US-20230203087-A1 | OLIGONUCLEOTIDE COMPOSITIONS AND METHODS THEREOF | WAVE LIFE SCIENCES LTD. (SG) | 2023-06-29 | — | — | US | disclosed |