Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GNAI3 | P08754 | 3/20 | 0.34 |
| ▸ | GNAO1 | P09471 | 3/20 | 0.34 |
| ▸ | GNAI1 | P63096 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | GBA1 | P04062 | 1/20 | 0.34 |
| ▸ | SOAT1 | P35610 | 3/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | EEF2K | O00418 | 1/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | SOAT2 | O75908 | 1/20 | 0.32 |
| ▸ | MGLL | Q99685 | 1/20 | 0.32 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25751626 | 0.87 | HTT (0.37) | GNAI3GNAO1GNAI1KDM4EGAA | |
| SCHEMBL25766567 | 0.84 | MEN1 (0.35) | MEN1KMT2A | |
| SCHEMBL25751618 | 0.79 | MEN1 (0.39) | MEN1KMT2A | |
| SCHEMBL25751683 | 0.79 | ALDH1A1 (0.37) | GNAI3GNAO1GNAI1KDM4EGAA | |
| SCHEMBL25751673 | 0.79 | ALDH1A1 (0.37) | GNAI3GNAO1GNAI1KDM4EGAA | |
| SCHEMBL25751625 | 0.79 | ALDH1A1 (0.37) | GNAI3GNAO1GNAI1KDM4EGAA | |
| SCHEMBL25751668 | 0.79 | ALDH1A1 (0.37) | GNAI3GNAO1GNAI1KDM4EGAA | |
| SCHEMBL24052066 | 0.77 | GNAI3 (0.38) | GNAI3GNAO1GNAI1KDM4EGAA | |
| SCHEMBL25767156 | 0.76 | MEN1 (0.37) | MEN1KMT2A | |
| SCHEMBL25751617 | 0.75 | MEN1 (0.36) | MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230203484-A1 | DOUBLE STRANDED OLIGONUCLEOTIDE COMPOSITIONS AND METHODS RELATING THERETO | WAVE LIFE SCIENCES LTD. (SG) | 2023-06-29 | — | — | US | disclosed |