Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25766673 | 0.84 | LMNA (0.40) | LMNAALOX15ALDH1A1 | |
| SCHEMBL25751642 | 0.78 | LMNA (0.45) | LMNAALOX15ALDH1A1 | |
| SCHEMBL25766975 | 0.77 | LMNA (0.41) | LMNAALOX15ALDH1A1 | |
| SCHEMBL25767374 | 0.76 | LMNA (0.36) | LMNAALOX15ALDH1A1 | |
| SCHEMBL25751640 | 0.76 | LMNA (0.42) | LMNAALOX15ALDH1A1 | |
| SCHEMBL14580375 | 0.71 | LMNA (0.45) | LMNAALOX15ALDH1A1 | |
| SCHEMBL25751639 | 0.70 | INMT (0.39) | LMNAALOX15 | |
| SCHEMBL23806405 | 0.69 | LMNA (0.42) | LMNAALOX15ALDH1A1 | |
| SCHEMBL24052113 | 0.68 | LMNA (0.49) | LMNAALOX15ALDH1A1 | |
| SCHEMBL14318293 | 0.67 | LMNA (0.45) | LMNAALOX15ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240026358-A1 | OLIGONUCLEOTIDE COMPOSITIONS AND METHODS THEREOF | WAVE LIFE SCIENCES LTD. (SG) | 2024-01-25 | — | — | US | disclosed |
| US-20230203484-A1 | DOUBLE STRANDED OLIGONUCLEOTIDE COMPOSITIONS AND METHODS RELATING THERETO | WAVE LIFE SCIENCES LTD. (SG) | 2023-06-29 | — | — | US | disclosed |