Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RET | P07949 | 16/20 | 0.40 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.38 |
| ▸ | TTK | P33981 | 1/20 | 0.38 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.37 |
| ▸ | AR | P10275 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25757534 | 0.84 | EGLN2 (0.34) | RETTTKEGLN2AR | |
| SCHEMBL30895110 | 0.84 | DGAT1 (0.35) | — | |
| SCHEMBL30895038 | 0.84 | ITGA4 (0.36) | — | |
| SCHEMBL25757843 | 0.83 | PCSK9 (0.33) | RETTTKEGLN2AR | |
| SCHEMBL25757793 | 0.83 | NR1I2 (0.34) | — | |
| SCHEMBL30895044 | 0.82 | PCSK9 (0.36) | — | |
| SCHEMBL25757792 | 0.82 | ATR (0.35) | — | |
| SCHEMBL25757841 | 0.82 | ATR (0.35) | — | |
| SCHEMBL25757107 | 0.82 | ATR (0.42) | — | |
| SCHEMBL25757842 | 0.81 | IDO1 (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118401516-A | TYK2 inhibitors, compositions and methods thereof | 凌科药业(杭州)有限公司 | 2024-07-26 | — | — | CN | disclosed |
| WO-2023109954-A1 | TYK2 INHIBITORS AND COMPOSITIONS AND METHODS THEREOF | LYNK PHARMACEUTICALS CO. LTD. (CN) | 2023-06-22 | — | — | WO | disclosed |