Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.46 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.46 |
| ▸ | ESRRG | P62508 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.40 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | PLK1 | P53350 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11985612 | 0.88 | EPHX2 (0.46) | EPHX2ESRRGSMN1; SMN2ALDH1A1MAPK1 | |
| SCHEMBL11985608 | 0.81 | HDAC3 (0.48) | SMN1; SMN2ALDH1A1LMNAKDM4EKMT2A | |
| SCHEMBL18659081 | 0.81 | PLK1 (0.56) | EPHX2NR1H4SMN1; SMN2PARP10ALDH1A1 | |
| SCHEMBL25767472 | 0.80 | HTT (0.52) | EPHX2NR1H4ESRRGSMN1; SMN2PARP10 | |
| SCHEMBL21016381 | 0.76 | EPHX2 (0.51) | EPHX2NR1H4ESRRGSMN1; SMN2PARP10 | |
| SCHEMBL21137664 | 0.75 | HDAC1 (0.43) | SMN1; SMN2ALDH1A1PLK1LMNAHTT | |
| SCHEMBL22524710 | 0.74 | KDM4E (0.50) | SMN1; SMN2ALDH1A1LMNAKDM4EKMT2A | |
| SCHEMBL11985627 | 0.74 | LMNA (0.39) | ALDH1A1HSD17B10TSHRRAB9ALMNA | |
| SCHEMBL11985607 | 0.74 | HDAC1 (0.52) | SMN1; SMN2ALDH1A1MAPK1NPC1RAB9A | |
| SCHEMBL28360034 | 0.73 | NPC1 (0.52) | EPHX2NR1H4ESRRGSMN1; SMN2PARP10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230203484-A1 | DOUBLE STRANDED OLIGONUCLEOTIDE COMPOSITIONS AND METHODS RELATING THERETO | WAVE LIFE SCIENCES LTD. (SG) | 2023-06-29 | — | — | US | disclosed |