Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 6/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 5/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 5/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | PLK1 | P53350 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | MLYCD | O95822 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.35 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.35 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.35 |
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22266817 | 0.87 | HDAC1 (0.44) | HDAC1HDAC3HDAC2HDAC8HDAC6 | |
| SCHEMBL25757213 | 0.75 | HDAC3 (0.51) | HDAC3HDAC8HDAC6MEN1MAPT | |
| SCHEMBL11985612 | 0.75 | EPHX2 (0.46) | MEN1ALDH1A1MAPTKMT2ASMN1; SMN2 | |
| SCHEMBL25754068 | 0.75 | EPHX2 (0.46) | HDAC1HDAC3HDAC2HDAC8HDAC6 | |
| SCHEMBL22832225 | 0.74 | POLB (0.50) | HDAC1HDAC3HDAC2HDAC8SMN1; SMN2 | |
| SCHEMBL22832224 | 0.74 | POLB (0.50) | HDAC1HDAC3HDAC2HDAC8SMN1; SMN2 | |
| SCHEMBL19271911 | 0.74 | NAAA (0.56) | HDAC1HDAC3HDAC2 | |
| SCHEMBL19951590 | 0.74 | NAAA (0.53) | HDAC1HDAC3HDAC2HDAC8SMN1; SMN2 | |
| SCHEMBL25754051 | 0.73 | CA2 (0.59) | MEN1KMT2ALMNAHTT | |
| SCHEMBL11985608 | 0.72 | HDAC3 (0.48) | HDAC1HDAC3HDAC2ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10329266-B2 | Protease inhibitors | MEDIVIR AB (SE) | 2019-06-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10329266-B2 | Protease inhibitors | CTSK, CTSF, CTSS | HDAC1 122/4885HDAC3 107/4885HDAC2 376/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.