Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | CSF1R | P07333 | 1/20 | 0.35 |
| ▸ | MAP2K1 | Q02750 | 3/20 | 0.34 |
| ▸ | BTK | Q06187 | 2/20 | 0.34 |
| ▸ | CDC7 | O00311 | 1/20 | 0.34 |
| ▸ | PLK4 | O00444 | 1/20 | 0.34 |
| ▸ | AURKA | O14965 | 1/20 | 0.34 |
| ▸ | RPS6KA4 | O75676 | 1/20 | 0.34 |
| ▸ | CDKL5 | O76039 | 1/20 | 0.34 |
| ▸ | STK10 | O94804 | 1/20 | 0.34 |
| ▸ | LATS1 | O95835 | 1/20 | 0.34 |
| ▸ | ABL1 | P00519 | 1/20 | 0.34 |
| ▸ | LCK | P06239 | 1/20 | 0.34 |
| ▸ | FYN | P06241 | 1/20 | 0.34 |
| ▸ | YES1 | P07947 | 1/20 | 0.34 |
| ▸ | LYN | P07948 | 1/20 | 0.34 |
| ▸ | RET | P07949 | 1/20 | 0.34 |
| ▸ | HCK | P08631 | 1/20 | 0.34 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14353015 | 0.94 | MAP2K1 (0.34) | MEN1KMT2ACSF1RMAP2K1BTK | |
| SCHEMBL15409478 | 0.93 | MAP2K1 (0.33) | MEN1KMT2AMAP2K1BTKCDC7 | |
| SCHEMBL15409472 | 0.93 | MAP2K1 (0.33) | MEN1KMT2AMAP2K1BTKCDC7 | |
| SCHEMBL25760681 | 0.91 | MAP2K1 (0.37) | MEN1KMT2AMAP2K1BTKCDC7 | |
| SCHEMBL25031703 | 0.88 | RET (0.36) | MEN1KMT2AMAP2K1BTKCDC7 | |
| SCHEMBL25780070 | 0.88 | MAP2K1 (0.38) | MEN1KMT2AMAP2K1BTKCDC7 | |
| SCHEMBL15406959 | 0.87 | MAP2K1 (0.37) | MEN1KMT2AMAP2K1BTKCDC7 | |
| SCHEMBL15423751 | 0.87 | MAP2K1 (0.37) | MEN1KMT2AMAP2K1BTKCDC7 | |
| SCHEMBL15406957 | 0.87 | MAP2K1 (0.37) | MEN1KMT2AMAP2K1BTKCDC7 | |
| SCHEMBL26907228 | 0.87 | MAP2K1 (0.48) | MAP2K1BTKCDC7PLK4AURKA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230210999-A1 | TARGETED PROTEASE DEGRADATION (TED) PLATFORM | EUBULUS BIOTHERAPEUTICS (HONG KONG) LIMITED (HK) | 2023-07-06 | — | — | US | disclosed |
| US-20230210999-A1 | TARGETED PROTEASE DEGRADATION (TED) PLATFORM | EUBULUS BIOTHERAPEUTICS (HONG KONG) LIMITED (HK) | 2023-07-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230210999-A1 | TARGETED PROTEASE DEGRADATION (TED) PLATFORM | UCHL3, UBE2L3, ADAM33 | MEN1 940/4885KMT2A 1974/4885CSF1R 2306/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.