Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 9/20 | 0.66 |
| ▸ | NPC1 | O15118 | 8/20 | 0.66 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.66 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.50 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.49 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.49 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.49 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | CASP1 | P29466 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19058585 | 0.84 | NPC1 (0.71) | RAB9ANPC1SMN1; SMN2TRPV1CHRNA7 | |
| SCHEMBL24052027 | 0.84 | RAB9A (0.71) | RAB9ANPC1SMN1; SMN2TRPV1MEN1 | |
| SCHEMBL2409590 | 0.82 | HDAC6 (0.58) | RAB9ANPC1SMN1; SMN2TRPV1HDAC6 | |
| SCHEMBL31120903 | 0.81 | NPC1 (0.71) | RAB9ANPC1SMN1; SMN2TRPV1MEN1 | |
| SCHEMBL2970236 | 0.81 | NPC1 (0.71) | RAB9ANPC1SMN1; SMN2TRPV1MEN1 | |
| SCHEMBL25753501 | 0.80 | NPC1 (0.66) | RAB9ANPC1SMN1; SMN2TRPV1MEN1 | |
| SCHEMBL1105986 | 0.80 | NPC1 (1.00) | RAB9ANPC1SMN1; SMN2TRPV1MEN1 | |
| SCHEMBL4986940 | 0.79 | TRPV1 (0.62) | RAB9ANPC1SMN1; SMN2TRPV1MEN1 | |
| SCHEMBL25766322 | 0.79 | NPC1 (0.64) | RAB9ANPC1SMN1; SMN2TRPV1MEN1 | |
| SCHEMBL20481983 | 0.79 | NPC1 (0.78) | RAB9ANPC1SMN1; SMN2TRPV1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240026358-A1 | OLIGONUCLEOTIDE COMPOSITIONS AND METHODS THEREOF | WAVE LIFE SCIENCES LTD. (SG) | 2024-01-25 | — | — | US | disclosed |
| US-20230203484-A1 | DOUBLE STRANDED OLIGONUCLEOTIDE COMPOSITIONS AND METHODS RELATING THERETO | WAVE LIFE SCIENCES LTD. (SG) | 2023-06-29 | — | — | US | disclosed |