SCHEMBL25754267

SCHEMBL25754267

CC#CCCNCCOCCC

nearest known ligand 0.32

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.32
KDM4E B2RXH2 1/20 0.31
RECQL P46063 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25754297 0.94 TSHR (0.33) TSHR
SCHEMBL25754292 0.87 TSHR (0.33) TSHR
SCHEMBL25754295 0.85 TSHR (0.35) TSHR
SCHEMBL241373 0.80 TSHR (0.40) TSHRKDM4ERECQL
SCHEMBL25754281 0.78 CA12 (0.31) TSHRRECQL
SCHEMBL5932102 0.78 TSHR (0.43) TSHRKDM4ERECQL
SCHEMBL10959162 0.78 TSHR (0.43) TSHRKDM4ERECQL
SCHEMBL25754301 0.76 KDM4E (0.38) TSHRKDM4E
SCHEMBL15788000 0.75 TSHR (0.38) TSHRKDM4ERECQL
SCHEMBL25754276 0.74

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230210999-A1 TARGETED PROTEASE DEGRADATION (TED) PLATFORM EUBULUS BIOTHERAPEUTICS (HONG KONG) LIMITED (HK) 2023-07-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230210999-A1 TARGETED PROTEASE DEGRADATION (TED) PLATFORM UCHL3, UBE2L3, ADAM33 TSHR 331/4885KDM4E 2658/4885RECQL 1284/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.