Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNQ3 | O43525 | 1/20 | 0.36 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.36 |
| ▸ | P2RX3 | P56373 | 4/20 | 0.36 |
| ▸ | TRPV3 | Q8NET8 | 1/20 | 0.34 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.33 |
| ▸ | NAAA | Q02083 | 1/20 | 0.33 |
| ▸ | FFAR4 | Q5NUL3 | 6/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.32 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9228799 | 0.84 | KMT2A (0.31) | MEN1MAPTKMT2AALDH1A1 | |
| SCHEMBL178391 | 0.81 | CA12 (0.47) | P2RX3MAOBMEN1MAPTKMT2A | |
| SCHEMBL4010865 | 0.80 | TDP1 (0.36) | CSNK2A1FFAR4MAPTHPGDKMT2A | |
| SCHEMBL23218 | 0.79 | RAB9A (0.46) | NAAAMEN1MAPTKMT2AL3MBTL1 | |
| SCHEMBL8417 | 0.79 | ALDH1A1 (0.40) | TRPV3FFAR4KMT2AALDH1A1ALDH1A3 | |
| SCHEMBL4012282 | 0.79 | CSNK2A1 (0.51) | CSNK2A1MEN1KMT2A | |
| SCHEMBL2997372 | 0.77 | KCNK3 (0.39) | CSNK2A1 | |
| SCHEMBL19644906 | 0.75 | CYP11B1 (0.43) | TRPV3NAAAFFAR4MAOB | |
| SCHEMBL177773 | 0.75 | KDM1A (0.46) | KCNQ3KCNQ2MAPTL3MBTL1 | |
| SCHEMBL5745812 | 0.75 | MEN1 (0.50) | KCNQ3KCNQ2P2RX3TRPV3CSNK2A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2384327-A1 | FUSED RING COMPOUND AND USE THEREOF | Takeda Pharmaceutical Company Limited (JP) | 2011-11-09 | — | — | EP | disclosed |
| WO-2010087515-A1 | FUSED RING COMPOUND AND USE THEREOF | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-08-05 | — | — | WO | disclosed |