Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | GGPS1 | O95749 | 3/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25754349 | 0.98 | SPHK1 (0.33) | SPHK1HSD17B10GGPS1 | |
| SCHEMBL25754381 | 0.91 | SPHK1 (0.33) | SPHK1HSD17B10 | |
| SCHEMBL25754344 | 0.89 | HSD17B10 (0.33) | HSD17B10 | |
| SCHEMBL25754363 | 0.82 | — | — | |
| SCHEMBL25754360 | 0.81 | — | — | |
| SCHEMBL25754735 | 0.77 | HRH3 (0.36) | — | |
| SCHEMBL25754749 | 0.77 | HRH3 (0.38) | — | |
| SCHEMBL22526551 | 0.73 | PIK3CD (0.50) | SPHK1HSD17B10GGPS1 | |
| SCHEMBL25754230 | 0.72 | USP2 (0.44) | SPHK1HSD17B10 | |
| SCHEMBL25754242 | 0.72 | USP2 (0.49) | SPHK1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230210999-A1 | TARGETED PROTEASE DEGRADATION (TED) PLATFORM | EUBULUS BIOTHERAPEUTICS (HONG KONG) LIMITED (HK) | 2023-07-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230210999-A1 | TARGETED PROTEASE DEGRADATION (TED) PLATFORM | UCHL3, UBE2L3, ADAM33 | SPHK1 4450/4885HSD17B10 2815/4885GGPS1 4697/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.