⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25754488 | 0.86 | HSD17B10 (0.42) | — | |
| SCHEMBL25754480 | 0.83 | HTT (0.40) | — | |
| SCHEMBL25754490 | 0.78 | HTT (0.34) | — | |
| SCHEMBL25754487 | 0.77 | HTT (0.51) | — | |
| SCHEMBL25754498 | 0.73 | HRH3 (0.33) | — | |
| SCHEMBL25754237 | 0.72 | HTT (0.42) | — | |
| SCHEMBL17122964 | 0.71 | HTT (0.32) | — | |
| SCHEMBL25754356 | 0.70 | ADRB2 (0.33) | — | |
| SCHEMBL17148498 | 0.68 | HTT (0.33) | — | |
| SCHEMBL25754393 | 0.68 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230210999-A1 | TARGETED PROTEASE DEGRADATION (TED) PLATFORM | EUBULUS BIOTHERAPEUTICS (HONG KONG) LIMITED (HK) | 2023-07-06 | — | — | US | disclosed |