SCHEMBL25754521

SCHEMBL25754521

CC#CC(O)COCC(N)COCCN1CCCCC1

nearest known ligand 0.33

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.32
HRH3 Q9Y5N1 2/20 0.32
LMNA P02545 1/20 0.31
PSMB1 P20618 2/20 0.31
PSMB5 P28074 2/20 0.31
KDM4E B2RXH2 1/20 0.30
ALDH1A1 P00352 1/20 0.30
PSMB2 P49721 1/20 0.30
MEN1 O00255 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25754248 0.92 KMT2A (0.36) KMT2AHRH3PSMB1PSMB5KDM4E
SCHEMBL25754503 0.90 HRH3 (0.32) KMT2AHRH3LMNAPSMB1PSMB5
SCHEMBL25754252 0.89 KDM4E (0.38) KMT2AHRH3PSMB1PSMB5KDM4E
SCHEMBL25754504 0.85 HRH3 (0.31) HRH3LMNA
SCHEMBL25754526 0.85 KMT2A (0.37) KMT2AKDM4EALDH1A1MEN1
SCHEMBL25754506 0.85 KMT2A (0.38) KMT2AKDM4EALDH1A1MEN1
SCHEMBL25754498 0.82 HRH3 (0.33) KMT2AHRH3LMNAPSMB1PSMB5
SCHEMBL25754249 0.80 HRH3 (0.38) KMT2AHRH3PSMB1PSMB5KDM4E
SCHEMBL25754591 0.80 HRH3 (0.38) KMT2AHRH3PSMB1PSMB5KDM4E
SCHEMBL25754394 0.80 HRH3 (0.35) HRH3LMNAPSMB1PSMB5KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230210999-A1 TARGETED PROTEASE DEGRADATION (TED) PLATFORM EUBULUS BIOTHERAPEUTICS (HONG KONG) LIMITED (HK) 2023-07-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230210999-A1 TARGETED PROTEASE DEGRADATION (TED) PLATFORM UCHL3, UBE2L3, ADAM33 KMT2A 1974/4885HRH3 1596/4885LMNA 1517/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.