Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CARM1 | Q86X55 | 1/20 | 0.42 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.42 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.42 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.41 |
| ▸ | KDM1A | O60341 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
| ▸ | SCN5A | Q14524 | 2/20 | 0.37 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | CA12 | O43570 | 2/20 | 0.35 |
| ▸ | CA1 | P00915 | 2/20 | 0.35 |
| ▸ | CA2 | P00918 | 2/20 | 0.35 |
| ▸ | CA9 | Q16790 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25754655 | 0.92 | HRH3 (0.45) | CARM1PRMT6PRMT8KDM1ASIGMAR1 | |
| SCHEMBL25754680 | 0.88 | CARM1 (0.36) | CARM1PRMT6PRMT8ACE2KDM1A | |
| SCHEMBL25754653 | 0.85 | HRH3 (0.45) | CARM1PRMT6PRMT8KDM1ASIGMAR1 | |
| SCHEMBL25754677 | 0.85 | HRH3 (0.38) | CARM1PRMT6PRMT8SIGMAR1HRH3 | |
| SCHEMBL25754665 | 0.85 | CARM1 (0.36) | CARM1PRMT6PRMT8ACE2KDM1A | |
| SCHEMBL25754685 | 0.84 | HRH3 (0.40) | SIGMAR1HRH3SCN5A | |
| SCHEMBL25754658 | 0.81 | CARM1 (0.38) | CARM1PRMT6PRMT8ACE2KDM1A | |
| SCHEMBL6051858 | 0.79 | ACE2 (0.56) | CARM1PRMT6PRMT8ACE2KDM1A | |
| SCHEMBL25754671 | 0.79 | HRH3 (0.38) | CARM1PRMT6PRMT8SIGMAR1HRH3 | |
| SCHEMBL25754570 | 0.78 | HRH3 (0.60) | SIGMAR1HRH3MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230210999-A1 | TARGETED PROTEASE DEGRADATION (TED) PLATFORM | EUBULUS BIOTHERAPEUTICS (HONG KONG) LIMITED (HK) | 2023-07-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230210999-A1 | TARGETED PROTEASE DEGRADATION (TED) PLATFORM | UCHL3, UBE2L3, ADAM33 | CARM1 1753/4885PRMT6 1350/4885PRMT8 1536/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.