SCHEMBL2575466

SCHEMBL2575466

NN(O)c1cccc2ccccc12

nearest known ligand 0.53

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
SIGMAR1 Q99720 9/20 0.53
ALDH1A1 P00352 4/20 0.44
TSHR P16473 2/20 0.44
HSD17B10 Q99714 2/20 0.44
CYP1A2 P05177 2/20 0.44
CYP3A4 P08684 1/20 0.44
HPGD P15428 1/20 0.44
KEAP1 Q14145 1/20 0.44
CYP2A6 P11509 3/20 0.42
TDP1 Q9NUW8 1/20 0.42
L3MBTL1 Q9Y468 1/20 0.41
KMT2A Q03164 1/20 0.40
MMP9 P14780 1/20 0.40
KDM4E B2RXH2 1/20 0.39
GAA P10253 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7067991 0.81 SIGMAR1 (0.52) SIGMAR1ALDH1A1TSHRHSD17B10CYP1A2
SCHEMBL6509235 0.81 SIGMAR1 (0.52) SIGMAR1ALDH1A1TSHRHSD17B10CYP1A2
SCHEMBL4141823 0.81 SIGMAR1 (0.52) SIGMAR1ALDH1A1TSHRHSD17B10CYP1A2
SCHEMBL4965222 0.81 SIGMAR1 (0.57) SIGMAR1ALDH1A1TSHRHSD17B10CYP1A2
SCHEMBL29495790 0.77 SIGMAR1 (0.59) SIGMAR1ALDH1A1TSHRHSD17B10CYP1A2
Boric Acid SCHEMBL29084632 0.77 SIGMAR1 (0.53) SIGMAR1ALDH1A1TSHRHSD17B10CYP1A2
SCHEMBL3887404 0.77 SIGMAR1 (0.59) SIGMAR1ALDH1A1TSHRHSD17B10CYP1A2
SCHEMBL5842724 0.77 SIGMAR1 (0.64) SIGMAR1ALDH1A1TSHRHSD17B10CYP1A2
SCHEMBL29143191 0.77 SIGMAR1 (0.48) SIGMAR1ALDH1A1TSHRHSD17B10CYP1A2
SCHEMBL11672429 0.75 SIGMAR1 (0.56) SIGMAR1ALDH1A1TSHRHSD17B10CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107615166-A Photosensitive resin composition, method for producing polyimide, and semiconductor device 旭化成株式会社 2018-01-19 CN disclosed
US-20120270966-A1 Composition based on natural rubber and a reinforcing inorganic filler comprising dihydrazide MICHELIN RECHERCHE ET TECHNIQUE S.A. (CH) 2012-10-25 US disclosed
EP-2382264-A1 COMPOSITION BASED ON NATURAL RUBBER AND A REINFORCING INORGANIC FILLER COMPRISING A DIHYDRAZIDE Société de Technologie MICHELIN (FR) 2011-11-02 EP disclosed
WO-2010072762-A1 COMPOSITION BASED ON NATURAL RUBBER AND A REINFORCING INORGANIC FILLER COMPRISING A DIHYDRAZIDE SOCIETE DE TECHNOLOGIE MICHELIN (FR) 2010-07-01 WO disclosed